Comparing Liquid Versus Solid Forms of Sugars and Whey Protein

Obesity Clinical Trial

Official title:

Effect of Drinking Liquid Compared to Eating Solid Treatment of Sugars or Whey Protein on Short-term Appetite and Food Intake

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01348685
• Other study ID #: Solid and liquid 1
• Status: Completed
• Phase: N/A
• First received: May 4, 2011
• Last updated: May 4, 2011
• Start date: January 2007
• Est. completion date: March 2009

Study information

• Verified date: February 2011
• Source: University of Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Interventional

Clinical Trial Summary

To compare the effect of eating solid vs. drinking liquid forms of gelatin, sucrose and its component mixtures and whey protein on subjective appetite and food intake in young men.

Description:

Three randomized cross-over design experiments were used to compare the effect of solid and liquid forms of gelatin (6 g) in experiment 1, sucrose (75 g) and a mixture of 50% glucose/ 50% fructose (G50:F50) in experiment 2, and acid and sweet whey protein (50 g) in experiment 3 on healthy normal weight males . The controls were water (experiment 1 and 3) and calorie-free sweetened water with gelatin (sweet gelatin, experiment 1) or without gelatin (sweet control, experiment 2). Subjective average appetite was measured by visual analogue scales frequently over 1 h and ad libitum food intake was measured 1 h after the treatment consumptions.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 43
• Est. completion date: March 2009
• Est. primary completion date: March 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 19 Years to 28 Years

Eligibility

Inclusion Criteria:

• Healthy lean males with BMI between 18- 24.9 kg/m2 and an age range of 19 to 28 years were recruited for the three experiments.

Exclusion Criteria:

• Diabetics (fasting blood glucose = 7.0 mmol/L), smokers, breakfast skippers or dieters were excluded from the experiments. Individuals under medications or with a history of liver or kidney disease and major medical or surgical event within the last six months were excluded.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Diabetes
• Obesity

Intervention

Other:
• Compare the effect of solid vs. liquid forms of sugars on satiety and food intake

• the effect of solid vs. liquid forms of gelatin on appetite and food intake

• The effect of solid vs. liquid forms of whey protein on food intake

Locations

Country	Name	City	State
Canada	University of Toronto, Department of Nutritional Sciences	Toronto	Ontario

Sponsors (4)

Lead Sponsor	Collaborator
University of Toronto	Canadian Sugar Institute, Mondelez International, Inc., Natural Sciences and Engineering Research Council, Canada

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	subjective appetite and short term food intake		60 min	No