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Fibre and Appetite Regulation Trial (FART)

Obesity Clinical Trial

Official title:
Long-term Effect of Cereal Fibre on Abdominal Fat in Insulin Resistant Subjects

Clinical Trial Summary

High intake of cereal fibre has been shown to be associated with reduced weight gain and improved insulin sensitivity. We hypothesize these effects are due to the short chain fatty acids derived from the bacterial fermentation (breakdown) of fibre in the colon (large intestine). Insulin resistant subjects will be randomized to receive 2 servings of a low-fibre cereal (eg. puffed rice) or 2 servings of a high-fibre cereal (wheat bran cereal) per day for one year. The effects of the diets on body weight, appetite, abdominal fat, blood short chain fatty acids, glucose, insulin, lipids and hormones will be measured

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00247455
Study type Interventional
Source University of Toronto
Contact
Status Completed
Phase N/A
Start date March 2002
Completion date August 2005
View Details
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