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Clinical Trial Summary

The purpose of this study is to understand how the opioid system is involved in eating behavior.


Clinical Trial Description

Obesity is associated with greater risk for cardiovascular disease (CVD), stroke, diabetes, and mortality, and is a heterogeneous condition with various causes and thus a diversity of intervention targets. Compulsive overeating afflicts 30% of people seeking obesity treatment and increases risk for CVD factors. This trial involves two participant visits to test whether opioid blockade (Day 1 or 2, depending on randomization), compared to placebo (Day 1 or 2, depending on randomization), will elicit common symptoms of opioid withdrawal, including nausea. Participants will receive each condition on separate days. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02805972
Study type Interventional
Source University of California, San Francisco
Contact
Status Completed
Phase Phase 2
Start date May 20, 2017
Completion date July 25, 2018

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