Clinical Trials Logo
  1. Home
  2. Obesity Hypoventilation Syndrome
  3. NCT01757444

Non Invasive Ventilation : Efficacy of a New Ventilatory Mode in Patients With OHS

Obesity Hypoventilation Syndrome Clinical Trial

Official title:
Clinical Benefits and Tolerance to a New Ventilatory Mode in Patients With Obesity Hypoventilation Syndrome (OHS).

Clinical Trial Summary

In 2012, it has announced the availability of the new ventilator (BiPAP- A40), which could offer potential advantages over fixed level pressure support, in particular, in patients with obesity hypoventilation syndrome (OHS). One of the key benefits of the BiPAP A40 is an innovative ventilation mode called AVAPS-AE, which automatically maintains airway patency while delivering the correct level of ventilation each user requires, whatever their body position or sleep stage. AVAPS-AE mode is also aimed to help the clinicians during the initial titration of therapy, while providing long term comfort and assuring therapy compliance. However, studies on the physiologic and clinical effects have not yet been performed. The aim of our singled-blind randomised multicentre controlled trial is to prospectively investigate the effects of BiPAP with the spontaneous/timed (S/T) or the AVAPS-AE ventilation mode over 8 weeks on sleep quality, ventilation pattern, gas exchange, symptoms, body composition, level of physical activity and health-related quality of life in OHS patients.

Clinical Trial Description

Efficacy on sleep quality, symptoms, physical activity and quality of life ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01757444
Study type Interventional
Source Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Contact
Status Completed
Phase N/A
Start date June 2013
Completion date September 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT01903135 - Prevalence of Obesity Hypoventilation Syndrome N/A
Recruiting NCT04098094 - Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Withdrawn NCT03861468 - Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS ) N/A
Completed NCT01368614 - AVAPS-AE Efficacy Study N/A
Terminated NCT01964339 - Obesity Hypoventilation Syndrome Prevalence Study
Completed NCT04108819 - Ketogenic Diet for Obesity Hypoventilation Syndrome N/A
Completed NCT02934581 - Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units
Terminated NCT03353064 - Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure N/A
Completed NCT03085537 - Effectiveness Monitoring of Home Non-invasive Mechanical Ventilation by Digital Diagnosis Platform
Recruiting NCT02980770 - Postoperative Complications in Patients With Obesity Hypoventilation Syndrome N/A
Completed NCT01483716 - A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS) N/A
Completed NCT01499485 - Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation. Phase 3
Completed NCT03506906 - The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation N/A
Terminated NCT02317042 - Juno Perth Clinical Trial N/A
Withdrawn NCT01104610 - Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome N/A
Completed NCT01405976 - Alternative of Treatment in Obesity Hypoventilation Syndrome N/A
Recruiting NCT03854058 - Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease
Not yet recruiting NCT05190458 - Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap Syndrome N/A
Recruiting NCT04100616 - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity
Completed NCT02342899 - Cost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure Phase 3