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Obese clinical trials

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NCT ID: NCT04299854 Completed - Obese Clinical Trials

Modality of Induction of Labor in Obese Women at Term (MODOBAT)

MODOBAT
Start date: June 11, 2020
Phase:
Study type: Observational

In normal-weight patients, numerous studies show an equivalence of efficacy between dinoprostone and balloon to induce labor. In obese patients, this efficacy is not known, although inductions of labor are more frequent. MODOBAT aims to describe the ability to obtain a vaginal delivery of two modality of induction of labor (vaginal dinoprostone and single balloon Foley catheter) in obese women at term.

NCT ID: NCT04234295 Completed - Healthy Clinical Trials

Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue

Start date: January 29, 2020
Phase: N/A
Study type: Interventional

Researchers are trying to better understand the relationship between inflammation in adipose tissue (AT) and insulin resistance.

NCT ID: NCT04115657 Completed - Obese Clinical Trials

The Effect of Different Starches of Boba Pearls and Sugar Substitutes Used in Milk Tea on Glycaemia, Insulinaemia and Appetite Control (Pearl Study)

Start date: May 2, 2019
Phase: N/A
Study type: Interventional

The first objective is to investigate the effect of boba pearls made from different starches on glycaemia, insulinaemia and appetite control. The second objective is to investigate the effects of various sugar blends of sucrose with sugar substitutes in milk tea on glycaemia, insulinaemia and appetite control.

NCT ID: NCT04105075 Completed - Copd Clinical Trials

COPD in Obese Patients

Start date: September 9, 2018
Phase:
Study type: Observational

The study included 176 patients with COPD. The first group included 88 normal weight patients with COPD: 71 men and 17 women, mean age 62.40 ± 8.83 years. The second group included 88 patients with COPD and obesity: 64 men and 24 women, mean age 62.94 ± 5.96 years. We assessed the frequency of COPD exacerbations in last 12 months, the severity of symptoms such as dyspnea, sputum production, fatigue. Spirometry, six-minute walk test and analysis of body tissue type composition were performed. BODE index was calculated. Levels of leptin, adiponectin, interleukins-4,6,8,10, interferon-γ, c-reactive protein (CRP), tumor necrosis factor receptor 1 (TNF-R1), tumor necrosis factor receptor 2 (TNF-R2), tumor necrosis factor alpha (TNF-α) were measured in blood serum.

NCT ID: NCT04099654 Completed - Exercise Clinical Trials

The Effect of Core Stabilization Exercise Program in Obese Subjects Awaiting Bariatric Surgery

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

In this study, our primary aim is to investigate the effects of structured core stabilization exercise program on functional capacity, body composition, muscle strength, endurance, balance, quality of life in adult obese individuals expecting bariatric surgery. Our secondary aim is to provide the individual with exercise habits and increase the level of physical activity in daily life with the exercise program planned according to the needs of the individual.

NCT ID: NCT04039685 Completed - Obesity Clinical Trials

The Effects of Chronic Exercise on UCP1 Gene in Human White Adipose Tissue

Start date: June 1, 2013
Phase: N/A
Study type: Interventional

Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk for disease. For this reason, previous research focused on the thermogenic capacity of white adipocytes in response to chronic exercise. It is suggested that the latter occurs due to increased demand of oxidation during exercise to maintain non-esterified fatty acids flux in the circulation, thus to maintain energy supply White adipocytes express the uncoupling protein one (UCP1), which dissipates chemical energy in the mitochondria to produce heat in response to cold exposure. UCP1 was thought that exclusively appears in brown adipose tissue (BAT), which during the mitochondrial electron transport chain process, bypasses the adenosine triphosphate (ATP) synthase to produce heat, as a thermoregulatory mechanism of maintaining body temperature. Its presence in white adipocytes, indicates a thermogenic capacity of WAT, which could lead to similar health benefits as those reported for increased BAT activity; mainly reduced body mass index (BMI) and fat mass, which designate body weight loss and reduced obesity phenotype. The investigators aimed to identify whether UCP1 in human WAT is altered by chronic exercise.

NCT ID: NCT04037371 Completed - Obesity Clinical Trials

Environmental Temperature and Human White Adipose Tissue

Start date: April 2, 2017
Phase:
Study type: Observational

Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk for disease. For this reason, previous research focused on the thermogenic capacity of white adipocytes in response to cold exposure. The investigators aimed to identify whether human WAT thermogenic activation could alter energy homeostasis and subsequently total body weight. The human WAT thermogenic capacity was assessed via Positron Emission Tomography/Computed Tomography (PET/CT) examination.

NCT ID: NCT03996668 Completed - Obese Clinical Trials

Effect of Compression Stockings on Cerebral Desaturation Events in Obese Patients Undergoing Shoulder Arthroscopy in the Beach Chair

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

The study compares the effect of thigh high compression stockings on cerebral desaturation events in patients undergoing shoulder arthroscopy in the beach chair position with a BMI greater than or equal to 30.

NCT ID: NCT03995264 Completed - Obese Clinical Trials

Ultrasound vs Palpation for Radial Artery Cannulation

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare the palpation technique with ultrasound guidance for radial artery cannulation for bariatic surgery.

NCT ID: NCT03907384 Completed - Obese Clinical Trials

Mat Pilates and Vascular Function in Obese Females

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.