Circulating Oxidative Stress and Gestational Hypertension. Study of the Evolution of Free-radical Markers of Oxidative Stress From Before to After Childbirth in Two Groups of Women: Normal Pregnancy and Pre-eclampsia.

Normal Pregnancy Clinical Trial

Status Completed

Clinical Trial Summary

The aim of this study is to explore a mechanism that could potentially explain why women with a pregnancy complicated by pre-eclampsia are described as having an increased risk of cardiovascular disease later in life.

If the hypothesis of this study turns out to be true, that is to say that women with pre-eclampsia have a higher level of oxidative stress than women with a normal pregnancy and that this difference persists after the delivery (6 months), a controlled randomized interventional study aiming to evaluate either therapeutic supplementation with antioxidant vitamins (Vit C and E) or modifications in diet could be envisaged.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator)

Related Conditions & MeSH terms

• Eclampsia
• Normal Pregnancy
• Pre-Eclampsia
• Pregnancy Complicated by Pre-eclampsia.

• NCT number: NCT01907620
• Study type: Interventional
• Source: Centre Hospitalier Universitaire Dijon
• Status: Completed
• Phase: N/A
• Start date: November 2010
• Completion date: November 2011