High-flow Nasal Cannula Flow Rates, Severe Bronchiolitis

Status Completed

Clinical Trial Summary

Objective: The investigators aimed to compare the heated humidified high-ﬂow nasal cannula (HHHFNC) flow rate of 1-L/kg/min (1L) with 2-L/kg/min (2L) in patients with severe bronchiolitis presenting to the pediatric emergency department.

Study design: The investigators performed a study in which all patients were allocated to receive these two flow rates. The primary outcome was admitted as treatment failure, which was defined as a clinical escalation in respiratory status. Secondary outcomes covered a decrease of respiratory rate (RR), heart rate (HR), the clinical respiratory score (CRS), rise of peripheral capillary oxygen saturation (SpO2) and rates of weaning, intubation and intensive care unit (ICU) admission.

Keywords: Bronchiolitis, Emergency department, High‑flow nasal cannula, Flow rate

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03859947
Study type	Observational
Source	Ege University
Contact
Status	Completed
Phase
Start date	May 10, 2017
Completion date	October 31, 2018

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