Effects of E-Cigarette Flavors on Adults TCORS 2.0

Status Completed

Clinical Trial Summary

This study looks at the effects of flavors when administered with nicotine in e-cigarettes in younger and older adult cigarette smokers.

Clinical Trial Description

This study looks at the effects of flavors when administered with nicotine in e-cigarettes in younger and older adult cigarette smokers. Regular cigarette smokers who do not want to quit smoking will be asked to complete 3 lab sessions in which they will use an e-cigarette and complete questionnaires. This will be followed by a two-week period where participants are asked to stop using cigarettes and other tobacco products and to only use the e-cigarettes provided. Researchers will examine the influence of flavors (sweet, cool, tobacco) on reward (liking/wanting) from e-cigs containing one of two nicotine concentrations (6 mg/ml, 18 mg/ml) following acute tobacco abstinence. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03635333
Study type	Interventional
Source	Yale University
Contact
Status	Completed
Phase	Phase 1
Start date	March 15, 2019
Completion date	July 12, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04284813` - Families With Substance Use and Psychosis: A Pilot Study	N/A
Completed	`NCT02511704` - Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette	Phase 1
Completed	`NCT04568395` - Acute Effects of TCIG vs ECIG in PLWH	N/A
Completed	`NCT03338933` - Neurobiology of Alcohol and Nicotine Co-Addiction
Completed	`NCT03634839` - Effects of E-cigarette Flavors on Youth TCORS 2.0	Phase 1
Recruiting	`NCT05515354` - Smoking Cessation and Menstrual Cycle Phase	Phase 4
Withdrawn	`NCT06259630` - Nicotine Virtual Reality Conditioned Place Preference	Phase 4
Recruiting	`NCT06170138` - Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users	N/A
Not yet recruiting	`NCT03264755` - Cortical Excitability and Role of rTMS in Nicotine Use Disorder	N/A
Recruiting	`NCT05766254` - Identify the Optimal TMS Target to Modulate Reward Activity	N/A
Completed	`NCT00330187` - Combined Pharmaco/Behavior Therapy in Adolescent Smokers	Phase 2
Completed	`NCT03438188` - Neural Basis of Eating Behavior in Abstinent Smokers	N/A
Completed	`NCT03194958` - Helping Poor Smokers Quit	N/A
Not yet recruiting	`NCT05932745` - Effects of Novel E-cigarette Constituents on Adults TCORS 3.0	N/A
Recruiting	`NCT04432064` - Temporal Interference Neurostimulation and Addiction	N/A
Recruiting	`NCT05181891` - Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking	Phase 2
Active, not recruiting	`NCT05897242` - A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults	N/A
Not yet recruiting	`NCT05994209` - Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors	Phase 1
Completed	`NCT03302026` - Real Time fMRI and Quitting Smoking	N/A
Terminated	`NCT03352609` - Accelerated rTMS for the Reduction of Nicotine Craving	N/A