Effects of E-cigarette Flavors on Youth TCORS 2.0

Status Completed

Clinical Trial Summary

This study is an examination of the influence of sweet and cooling flavors on the appeal and abuse potential of nicotine-containing e-cigarettes among susceptible youth.

Clinical Trial Description

Researchers will examine the influence of sweet and cooling flavors on the appeal and abuse potential of nicotine-containing e-cigarettes among susceptible youth. Participants will rate the flavor intensity, coolness, sweetness, and irritation experienced using validated rating scales. Forty youth (18-20 years of age) who have experience with e-cigarettes and will participate in 1 laboratory session. They will receive 1 nicotine concentrations (36mg/ml nicotine salt) during the session; during the session they will be exposed, in random order, to sweet (watermelon) and sweet-cooling (watermelon-menthol) flavors combined with the assigned session nicotine concentration. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03634839
Study type	Interventional
Source	Yale University
Contact
Status	Completed
Phase	Phase 1
Start date	November 7, 2022
Completion date	July 20, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04284813` - Families With Substance Use and Psychosis: A Pilot Study	N/A
Completed	`NCT02511704` - Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette	Phase 1
Completed	`NCT04568395` - Acute Effects of TCIG vs ECIG in PLWH	N/A
Completed	`NCT03338933` - Neurobiology of Alcohol and Nicotine Co-Addiction
Recruiting	`NCT05515354` - Smoking Cessation and Menstrual Cycle Phase	Phase 4
Withdrawn	`NCT06259630` - Nicotine Virtual Reality Conditioned Place Preference	Phase 4
Recruiting	`NCT06170138` - Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users	N/A
Not yet recruiting	`NCT03264755` - Cortical Excitability and Role of rTMS in Nicotine Use Disorder	N/A
Recruiting	`NCT05766254` - Identify the Optimal TMS Target to Modulate Reward Activity	N/A
Completed	`NCT00330187` - Combined Pharmaco/Behavior Therapy in Adolescent Smokers	Phase 2
Completed	`NCT03635333` - Effects of E-Cigarette Flavors on Adults TCORS 2.0	Phase 1
Completed	`NCT03438188` - Neural Basis of Eating Behavior in Abstinent Smokers	N/A
Completed	`NCT03194958` - Helping Poor Smokers Quit	N/A
Not yet recruiting	`NCT05932745` - Effects of Novel E-cigarette Constituents on Adults TCORS 3.0	N/A
Recruiting	`NCT04432064` - Temporal Interference Neurostimulation and Addiction	N/A
Recruiting	`NCT05181891` - Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking	Phase 2
Active, not recruiting	`NCT05897242` - A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults	N/A
Not yet recruiting	`NCT05994209` - Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors	Phase 1
Completed	`NCT03302026` - Real Time fMRI and Quitting Smoking	N/A
Terminated	`NCT03352609` - Accelerated rTMS for the Reduction of Nicotine Craving	N/A