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Clinical Trial Summary

This study will assess the safety and efficacy of avutometinib (VS-6766) and defactinib in combination with gemcitabine and nab-paclitaxel in patients with Pancreatic Ductal Adenocarcinoma (PDAC) who have been previously untreated.


Clinical Trial Description

This is a multicenter, non-randomized, open-label Phase 1/2 study designed to evaluate safety, tolerability and efficacy of avutometinib (VS-6766) and defactinib in combination with gemcitabine and nab-paclitaxel in patients previously untreated metastatic Pancreatic Ductal Adenocarcinoma (PDAC). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05669482
Study type Interventional
Source Verastem, Inc.
Contact Verastem Call Center
Phone 1 781 292 4204
Email clinicaltrials@verastem.com
Status Recruiting
Phase Phase 1/Phase 2
Start date March 22, 2023
Completion date December 31, 2025

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