Neonatal Hypoxia and Asphyxia Clinical Trial
Official title:
Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Patients were classified into two equal groups using the presence or absence of hypertension during pregnancy into: hypertensive group (BP>140/90) and normotensive group (BP≤140/90. The surgical time intervals are assessed and classified the patients accordingly into short and log time interval subgroups (induction of regional anesthesia to delivery (I-D), initial skin incision to delivery (S-D), and uterine incision to delivery (U-D)
Surgical times components; induction of regional anesthesia till delivery (I-D interval);
incision of the skin till delivery (S-D interval); and incision of the uterus till delivery
(U-D interval)) were recorded using a stopwatch.
Immediately after delivery, umbilical cords were clamped on both ends and an arterial blood
sample was collected anaerobically in a pre-heparinized insulin syringe. PH, base excess
(BE), carbon dioxide pressure (PCO2), Oxygen pressure (PO2) and Bicarbonate (HCO3) levels
were measured at 37oC by pH and gas analyzer (Gem, Premier3000, USA). The gas analysis was
done in less than 30 minutes after sampling.
Apgar score was assessed by a neonatologist at the 1st and 5th minutes after birth . Advanced
resuscitation included positive pressure ventilation, chest compression and/or drugs
administration. All resuscitated babies were transferred to neonatal intensive care unit for
post resuscitation care. Fetal distress was defined by an umbilical cord pH <7.12
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