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Clinical Trial Summary

The investigators designed this study to investigate the effect of aromatase inhibitors (AI) plus chemotherapy versus chemotherapy as neoadjuvant treatment in postmenopausal hormone receptor-positive breast cancer.


Clinical Trial Description

The endocrine therapy has been used more and more in neoadjuvant treatment of hormone receptor-positive breast cancer. But it still a question if neoadjuvant endocrine therapy can be used combined with chemotherapy. There have been several small-sample studies concerning about this item and also got some results that support the suppose that endocrine therapy combined with chemotherapy could rise the effect of neoadjuvant treatment. This study is to investigate the effect of aromatase inhibitors (AI) plus chemotherapy versus chemotherapy as neoadjuvant treatment in postmenopausal hormone receptor-positive breast cancer. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02769104
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Hong-Jian Yang, MD.
Email yhjzlyy@163.com
Status Recruiting
Phase Phase 3
Start date May 2016
Completion date December 2019

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