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Nausea clinical trials

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NCT ID: NCT01055236 Completed - Nausea Clinical Trials

Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients

TAH
Start date: August 2007
Phase: Phase 4
Study type: Interventional

Hydroxyzine is one of antihistamines that antagonizes H1 receptor, and it's effects are reducing pruritus, nausea/vomiting, and the mild effect of sedation.With these effects Hydroxyzine should be used in the prevention of these symptoms.

NCT ID: NCT01054456 Completed - Clinical trials for Patients With Confirmed Malignant Disease to Receive Low Emetogenic Chemotherapy (LEC) or Who Experienced at Least Nausea and Vomiting During Last Cycle of LEC

A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Who Have Experienced CINV(Chemotherapy-Induced Nausea and Vomiting) During the Previous Cycle of Low Emetogenic Chemotherapy (LEC)

Start date: October 27, 2009
Phase: Phase 2
Study type: Interventional

This study is designed to assess the safety and efficacy of palonesetron in preventing chemotherapy-induced nausea and vomiting (CINV) when administered to participants who have experienced either vomiting and or at least moderate nausea during their last cycle of low emetogenic chemotherapy.

NCT ID: NCT01047371 Completed - Pain Clinical Trials

Why in Hospital - Factors Determining Time to Discharge Readiness After Arthroplasty Surgery

Start date: January 2010
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate patient related factors determining length of stay in hospital after arthroplasty surgery.

NCT ID: NCT01036854 Completed - Nausea Clinical Trials

Pharmacokinetic Study of Ondansetron Administered as IR (Zofran) and MR (EUR1025)

Start date: February 2009
Phase: Phase 1
Study type: Interventional

The objective of the study is to assess blood levels of ondansetron (EUR1025 24 mg) dose and Zofran 8 mg dose after single and multiple doses are given when taken with a meal and taken on an empty stomach.

NCT ID: NCT01031498 Completed - Clinical trials for Acute Myelogenous Leukemia

Palonosetron Versus Ondansetron for the Prevention of Nausea and Vomiting

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to compare the effectiveness of 3 drug schedules in preventing chemotherapy-related nausea and/or vomiting in patients with acute myelogenous leukemia (AML) or high-risk myelodysplastic syndrome (MDS).

NCT ID: NCT01020903 Completed - Clinical trials for Postoperative Nausea

Aprepitant for Post-operative Nausea

Start date: November 2009
Phase: N/A
Study type: Interventional

Anesthesia, especially for laparoscopic surgery, can cause post-operative nausea and vomiting. Most patients are given two drugs, decadron and ondansetron, to try to minimize this. This study is to determine if a new drug, aprepitant, would add any benefit in terms of post-op nausea prevention. All laparoscopic cholecystectomy study patients will receive decadron and ondansetron. Half the patients will receive aprepitant in addition. The other half will receive placebo. The study will be randomized and double-blind.

NCT ID: NCT01018758 Completed - Clinical trials for Chemotherapy-Induced Nausea and Vomiting

Study With Palonosetron Alone in Preventing Chemotherapy-induced Nausea and Vomiting in Untreated Patients With Aggressive Non Hodgkin's Lymphomas Who Underwent Moderately Emetogenic Chemotherapy

NHLPal
Start date: July 2006
Phase: Phase 2
Study type: Interventional

This is an open-label, multicenter phase II study in patients with aggressive Non Hodgkin Lymphoma scheduled to receive moderately emetogenic polychemotherapy (according to modified Hesketh classification for antiemetic therapy).

NCT ID: NCT01013012 Completed - Nausea Clinical Trials

Efficacy of Dexamethasone Added to Ramosetron for Preventing Postoperative Nausea and Vomiting in Highly Susceptible Patients Following Spine Surgery

Start date: January 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to study the efficacy of dexamethasone added to ramosetron for preventing postoperative nausea and vomiting in highly susceptible patients following spine surgery.

NCT ID: NCT01012336 Completed - Ovarian Cancer Clinical Trials

Safety and Efficacy of Aprepitant, Ramosetron, and Dexamethasone for Chemotherapy-Induced Nausea and Vomiting in Patients With Ovarian Cancer Treated With Taxane/Carboplatin

Start date: May 2010
Phase: Phase 2
Study type: Interventional

The current recommended guideline for patients receiving moderately emetogenic chemotherapy (MEC) is the combination of a 5-HT3 receptor antagonist and corticosteroid. Incidence of chemotherapy induced nausea and vomiting (CINV) is approximately 50% in patients receiving MEC. An incidence rate of 25-38% for delayed emesis and 55-60% for delayed nausea has been observed. Hence, there is clearly a need for more effective prevention of CINV in patients receiving MEC, especially in women with ovarian carcinoma who are particularly susceptible to these symptoms. Therefore the investigators designed a study with the objective to evaluate if new combination (Aprepitant/Ramosetron/Dexamethasone) may improve actual CINV control in ovarian carcinoma patients treated with taxane/carboplatin.

NCT ID: NCT01007500 Completed - Nausea Clinical Trials

Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery

Start date: September 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.