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Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation

Myocardial Ischemia Clinical Trial

Official title:
Prospective Clinical Observational Study of Humanin Isoforms in Cardiac Muscle and Blood Plasma and Their Association to Major Complications After Cardiac Operation

Clinical Trial Summary

Objective of the study is to clarify humanin-like peptide concentration in myocard tissue and in blood and to study if its concentration level is related to early complication occurrence and frequency after cardiac operation.

Hypothesis of the study is that previously described elements are related to each other.

Clinical Trial Description

Data collection: Historical medical and preoperative data, operation data (type of operation performed and its details), detailed postoperative course (occurrence of complications).

Specimen collection:

- Tissue sample is taken during the operation from the right atrial appendage of the heart and the sample is frozen at -80 C.

- Blood samples are taken just before the operation, one hour after aortic cross-clamp removal and the next morning after the operation. Samples are processed and blood plasma is frozen at -80 C. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03431844
Study type Observational
Source University of Tartu
Contact
Status Completed
Phase
Start date January 1, 2018
Completion date August 31, 2019
View Details
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