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Effect of Timi3 Ultrasound on Myocardial Blow Flow in the Hibernating Myocardium

Myocardial Ischemia Clinical Trial

Official title:
Evaluation of the Effect of T3US on Myocardial Blow Flow in the Hibernating

Clinical Trial Summary

The purpose of this study is to evaluate whether the use application of low frequency ultrasound, administered by the Timi3 ultrasound device, increases myocardial blood flow to the heart, in subjects with reduced myocardial blood flow at rest (hibernating myocardium). The primary endpoint of the trial is to assess the increase in myocardial blood flow from baseline to post Timi3 Ultrasound treatment in a hypoperfused region of myocardium. Positron emission tomography (PET) imaging will be used to noninvasively evaluate cardiac blood flow. The hypothesis is that ultrasound increases blood flow in hibernating myocardium.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00655070
Study type Interventional
Source University of California, San Francisco
Contact
Status Terminated
Phase Phase 0
Start date April 2008
Completion date December 2010
View Details
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