Myocardial Injury Clinical Trial
— MIPSOfficial title:
Myocardial Infarction in the Perioperative Setting, a Swedish Multi Center Cohort Study
Verified date | February 2020 |
Source | Karolinska University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes after this complication.
Status | Completed |
Enrollment | 400742 |
Est. completion date | December 31, 2019 |
Est. primary completion date | December 31, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Adults (=18 years), male and female - Undergoing elective or non-elective inpatient noncardiac surgery Exclusion Criteria: - Cardiac surgery |
Country | Name | City | State |
---|---|---|---|
Sweden | Karolinska University Hospital | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Karolinska University Hospital |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Length of stay (LOS) | Time spent in the hospital (number of days) | LOS within the year after the index surgery | |
Other | Days at home alive within 30 days (DAH30) | Time spent in the home after the index surgery, takes into account readmissions | DAH30 is counted within 30days of the index surgery | |
Other | Risk of AMI and Mortality by gender, type of surgery, extent- and recency of comorbidity | How above mentioned patient characteristics affect risk of AMI and mortality | Within one year of the index surgery | |
Other | Secondary complications | AMI vs non-AMI patients and their risk of AKI, pneumonia, stroke, infections, thromboembolic complications | Secondary complications within one year of the index surgery | |
Other | Outcomes (AMI+Mortality+Complications) by hospital, region and year | All outcomes as affected by hospital type, region and by year | All outcomes within one year of the index surgery | |
Primary | Acute Myocardial Infarction | AMI, as detected in the postoperative phase in the electronic medical records or in the Swedeheart registry | Within 30days of the index surgery | |
Secondary | Mortality | Death, as detected in the postoperative phase in the Swedish cause of death register | Within 30days of the index surgery and at later predefined time points: 60, 90, 180 and 365 days after the index surgery |
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