Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.

Myocardial Infarction Clinical Trial

— ACR-MI  

Official title:

Factors Associated With Neurological Prognosis 30 Days After an ICU Admission for a Myocardial Infarction Complicated by an Out-of-Hospital Cardiac Arrest : an Observationnal Multicentric Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04584463
• Other study ID #: 2019PI166
• Status: Not yet recruiting
• Start date: October 30, 2020
• Est. completion date: November 30, 2021

Study information

• Verified date: October 2020
• Source: Central Hospital, Nancy, France
• Contact: BRUNO LEVY, MD-PHD
• Phone: 03 83 15 40 84
• Email: b.levy[@]chru-nancy.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study evaluate the association of some in-ICU factors with the neurological prognosis of patients admitted for an out-of-hospital cardiac arrest due to a myocardial infarction.

Description:

Pre-hospital factors associated with poor neurologic outcome are well known. Meanwhile, in-ICU factors for the first 24 hours may impact neurologic outcome.

This observational study aim to study the factors such as ECLS, NSE dosage, therapeutic hypotermia... and their association with neurologic outcome in patient with myocardial infarction due to instable coronaropathy complicated by an out-of-+hospital cardiac arrest.

This is designed to be a observationnal, prospective, multicentric national french study

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 110
• Est. completion date: November 30, 2021
• Est. primary completion date: October 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• aged of 18 years old or more

• non opposition of the patient, or his family if he is unable to consent, after loyal and comprehensive explanation

• patient admitted in ICU

• the reason for admission is a resurected out-of-hospital cardiac arrest

• the cause of the cardiac arrest is a type 1 myocardial infarction

Exclusion Criteria:

• refractory cardiac arrest (no flow > 30 minutes in normothermia)

• in-hospital cardiac arrest

• pregnancy

• patient under juridic protection

• opposition of the patient, or of his family is he is unable to consent.

Related Conditions & MeSH terms

• Coma
• Heart Arrest
• Infarction
• Myocardial Infarction
• Neurologic Dysfunction
• Neurologic Manifestations
• Out-of-Hospital Cardiac Arrest
• Outcome, Fatal

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Central Hospital, Nancy, France

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Neurologic outcome (CPC)	Cerebral Performance Category Scale to assess neurologic outcome 1-2 : good outcome 3-4-5 : bad outcome	30 day from in-ICU admission
Secondary	Neurologic outcome (Rankin)	Rankin score to assess neurologic outcome; 0-1-2 good outcome; 3-4-5 bad outcome	30 day from in-ICU admission
Secondary	death	all-causes death	30 day form in-ICU admission