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Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI)

Myocardial Infarction Clinical Trial

Official title:
Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction

Clinical Trial Summary

Based on accumulating evidences showing that hypothyroid status is associated with poor prognosis among acute myocardial infarction (AMI) patients, the study is designed to evaluate whether replacement treatment with levothyroxine could have beneficial effects on patients with AMI and hypothyroidism. This is a multicenter prospective computerized-randomized trial stratified by ejection fraction with a 1:1 ratio to levothyroxine group or standard therapy group.

Clinical Trial Description

The primary hypothesis is that reversing the hypothyroid status with levothyroxine on top of standard therapy for AMI is safe and has beneficial effects on cardiac function, myocardial perfusion/metabolism and myocardial fibrosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02512978
Study type Interventional
Source Chinese Academy of Medical Sciences, Fuwai Hospital
Contact Wen-Yao Wang, MD,PhD Candidate
Phone 8618810488381
Email wwypumc@126.com
Status Recruiting
Phase Phase 4
Start date August 2015
Completion date June 2019
View Details
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