Myocardial Infarction Clinical Trial
Official title:
Prognostic Value of Elevated Troponins in Critical Illness Study: A Pilot Study
Troponins are sensitive and specific markers of cardiac injury. Critically ill patients
frequently have elevated troponins. In this population, distinguishing patients with elevated
troponins from those with myocardial infarction is difficult. However, troponin elevations on
their own seem to be associated with an increased risk of death. The optimal treatment of
patients with type 2 myocardial infarction or non ischemia related troponin elevations during
critical illness is unclear. There are no trials in the ICU setting to guide management.
This study is a 1-month pilot cohort study of troponin screening in 4 Ontario intensive care
units. The objective of this pilot study is to evaluate the ability to perform a larger
study, which will determine the prevalence, incidence and risk factors for elevated troponin
values, how patients with elevated troponin values are treated as a baseline, and the
incidence of myocardial infarction in critically ill patients. Knowing the prognostic impact
of these conditions and understanding current management will thereafter guide researchers
and clinicians on the importance of carefully evaluating potential risk-modifying therapies.
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