Myocardial Infarction Clinical Trial
Official title:
Autologous Bone Marrow Derived Ac 133+ and Mono Nuclear Cells In-patient With Acute Myocardial Infarction During Coronary Artery Bypass Grafting (CABG): A Randomized Phase III Clinical Trial
One of the important reasons for human dying is Ischemic heart disease (IHD). The most
reason is coronary artery disease. Beside morbidity, IHD induce myocardial infarction and
necrosis which due to congestive heart failure.
One therapeutic method is cellular cardiomyoplasty, which is to produce and substitute the
cardiac cells with stem cell transplantation. Cell therapy is a potential therapeutic method
to prevent ventricular remodeling after acute myocardial infarction. Human and animal
studies have shown that stem cell trans plantation to myocardial infarcted zone can improve
heart contractile function.
The aim of this study is to comparison the effects of BM-derived AC133 and MNC implantation
in patients with myocardial infarction.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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