Myocardial Infarction Clinical Trial
Official title:
Leipzig Immediate Versus Early and Late PercutaneouS Coronary Intervention triAl in NSTEMI - LIPSIA-NSTEMI TRIAL
In non-ST-elevation the optimal time of percutaneous coronary intervention (PCI) is unclear.
Some studies showed benefit of very early PCI, some others early PCI between 12-48 hours and
others even showed a benefit of a selective invasive approach only in case of recurrence of
symptoms or a positive stress test.
The optimal timing of intervention is still matter of debate as a result of a randomized
clinical trial.
In this randomized, controlled, open-label clinical trial we compare a very early cardiac
catheterization (< 2,5 hours after randomization) similar to ST-elevation myocardial
infarction treatment, versus an early invasive approach (within 2-48 hours after
randomization) versus a selective invasive approach in patients with non-ST-elevation
myocardial infarction.
All patients are treated with heparin, ASA, Clopidogrel loading dose (600 mg) with
subsequent 75 mg/d and tirofiban for 24 hours.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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