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Clinical Trial Summary

Figure out the Efficacy and Safety of Azacitidine Combined with BUCY2 Conditioning Regimen Before Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome with Moderate High IPSS-M Score


Clinical Trial Description

This study is a prospective, single-center, single-arm clinical study, which plans to enroll 40 patients with high-risk myelodysplastic syndrome (MDS) to be given azacitidine (AZA) combined with busulfan and cyclophosphamide (BUCY2) conditioning regimen to evaluate 18-month progression-free survival (PFS), aiming to evaluate the efficacy and safety of azacitidine plus BUCY2 pretreatment regimen. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06279338
Study type Interventional
Source Wuhan Union Hospital, China
Contact Xiena Cao
Phone 0086-13031186262
Email caoxiena@126.com
Status Not yet recruiting
Phase N/A
Start date March 1, 2024
Completion date January 31, 2026

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