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Muscle Atrophy clinical trials

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NCT ID: NCT05382026 Recruiting - Muscle Atrophy Clinical Trials

Milk Versus a Pea-based Beverage for Bone and Muscle Health in Young Athletes

Start date: May 24, 2022
Phase: N/A
Study type: Interventional

Canada's Food Guide places an increased emphasis on plant-based proteins; however, Canadians who consume a plant-based diet may be compromised because of intake of lower-quality protein. Consumption of high-quality protein is important during growth and development, especially in highly active individuals. The study will compare milk (i.e. high quality protein) to a pea-based beverage (i.e. lower quality plant-based protein) in adolescent boys and girls who are engaged in resistance-training programs as part of their athletic training. One-hundred and fourteen adolescent boys and girls (12-17y of age) will be divided into groups that consume milk, a pea-beverage, or a carbohydrate (sugar) beverage after resistance training sessions performed three times per week for six months. It is predicted that the group consuming milk will have greater increases in muscle mass, strength, and bone density, and greater reductions in fat mass compared to the groups consuming a pea-based or carbohydrate beverages.

NCT ID: NCT05314413 Recruiting - Muscle Atrophy Clinical Trials

Examining Sex-based Differences in Metabolic and Mechanistic Responses to Disuse Induced Muscle Atrophy

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the proposed research is to define whether there are differences between females and males (i.e. sex-based differences) in the metabolic and mechanistic regulation of disuse-induced muscle atrophy in vivo in humans.

NCT ID: NCT05216666 Recruiting - Muscle Weakness Clinical Trials

The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty

HSS
Start date: May 11, 2022
Phase: N/A
Study type: Interventional

Residual limping after total hip arthroplasty is empirically associated with the use of lateral approach but has been reported in litterature even with the use of posterior approach. The purpose of this clinical trial is to compare the risk of residual limping one year after total hip arthropasty between lateral and posterior approach.

NCT ID: NCT05211986 Recruiting - Muscle Atrophy Clinical Trials

Safety and Tolerability of IMMUNA(IMM01-STEM) in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

Start date: September 13, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

An open-label dose escalation study to assess the safety and tolerability of IMMUNA(IMM01-STEM) in participants with muscle atrophy related to knee osteoarthritis

NCT ID: NCT05206838 Recruiting - Muscle Weakness Clinical Trials

Achilles Tendon for the Treatment of Gluteus Medius Insufficiency

HLS
Start date: June 29, 2022
Phase: N/A
Study type: Interventional

Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical treatment. Our hypothesis is that surgical treatment followed by physiotherapy increases hip function and reduces limping compared with non-surgical treatment with physiotherapy alone.

NCT ID: NCT05206253 Recruiting - Muscle Atrophy Clinical Trials

Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Start date: May 30, 2022
Phase: N/A
Study type: Interventional

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

NCT ID: NCT04900701 Recruiting - Aging Clinical Trials

The Impact of Energy Intake and Short-term Disuse on Muscle Protein Synthesis Rates and Skeletal Muscle Mass in Middle-aged Adults.

PIE
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

In healthy middle-aged men and women, what is the effect of dietary energy restriction and energy surplus on daily muscle protein synthesis rates and muscle morphology, compared to energy balance, during free-living and immobilisation?

NCT ID: NCT04849624 Recruiting - Covid19 Clinical Trials

Body Composition Study in Critically Ill Patients-Extended to COVID-19

COVID-MUSCLE
Start date: March 5, 2021
Phase:
Study type: Observational

Muscle loss (ultrasound quadricep muscle) and muscle strength (handgrip and knee extension strength) will be compared between COVID-19 and non COVID-19 critically ill patients.

NCT ID: NCT04742010 Recruiting - Bariatric Surgery Clinical Trials

Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS)

ZABAS
Start date: February 20, 2021
Phase: Phase 2
Study type: Interventional

In a randomised placebo-controlled trial assess effects of zoledronic acid for prevention of bone and muscle loss after bariatric surgery.

NCT ID: NCT04199936 Recruiting - Clinical trials for Postoperative Complications

Postoperative Electrical Muscle Stimulation (POEMS)

POEMS
Start date: November 18, 2020
Phase: N/A
Study type: Interventional

Patients lose a significant amount of muscle following major abdominal surgery. This is partly due to a catabolic response to the surgical insult and inflammation, but is also probably due to a lack of muscle use secondary to immobility. This study will aim to assess whether some or even all of postoperative muscle loss in the upper leg muscle group is preventable through electrical muscle stimulation to mimic physical activity.