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T and B Cell Responses in Autoimmune Diseases — SRA01  

Multiple Sclerosis Clinical Trial

Official title:
T and B Cell Responses Across Autoimmune Diseases

Clinical Trial Summary

The study aims to establish whether defects in immune cell function are shared across multiple autoimmune diseases and whether those problems match to similar genes in the cells.

Clinical Trial Description

This is a non-randomized, multi-center clinical research study. Subjects who are healthy or have a confirmed or suspected diagnosis of type 1diabetes, multiple sclerosis, psoriasis, Crohn's disease, or rheumatoid arthritis will be asked to donate a blood sample. No follow-ups are planned.

Investigators will:

- evaluate immune cells from subjects enrolled in this study and match the differences to types of immune cells known to cause autoimmune diseases

- investigate a particular disease pathway: the IL23R signaling cascade. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01947036
Study type Observational
Source National Institute of Allergy and Infectious Diseases (NIAID)
Contact
Status Terminated
Phase N/A
Start date January 2014
Completion date October 2015
View Details
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