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Clinical Trial Summary

The purpose of this study is to compare walking to leg strength and endurance in people with multiple sclerosis (PwMS). Using these findings, we hope to be better understand what causes PwMS to have problems walking.


Clinical Trial Description

The purposes of the research are to determine the association of gait performance with lower extremity muscle fatigability and strength measures, and create a preliminary model that can better explain the variance in gait performance based on these muscle performance values. Objective criterion-based measures of physical fatigue (i.e., fatigability) and muscle weakness have been associated with impaired task performance in people with multiple sclerosis (MS). MS-related deficits in muscle capacity result in higher fall risks and a loss of function. However, it is unclear if lower extremity fatigability tests add clinical value to objective strength testing in the rehabilitation and clinical management of MS. Better understanding how patterns of lower extremity (LE) fatigability and strength affect mobility in people with MS could improve outcome measure development and inform rehabilitation strategies. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03735654
Study type Observational
Source Washington D.C. Veterans Affairs Medical Center
Contact Michael Harris-Love, DSc
Phone (202) 745-8240
Email michael.harris-love@va.gov
Status Not yet recruiting
Phase
Start date November 15, 2018
Completion date October 1, 2021

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