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Clinical Trial Summary

The purpose of this study is to use genomic information from individual patients to create simulation avatars that will be used to predict novel drug combinations with therapeutic potential.


Clinical Trial Description

As part of normal clinical care, subjects will undergo peripheral blood draws and biopsies for disease assessment of their cancer. In cases of hematological malignancies, bone marrow aspiration & biopsy are routinely performed.

As part of this project, the following will be done to the samples collected and with clinical outcomes data:

- donate peripheral blood specimens whenever blood is already being drawn for clinical purposes.

- donate bone marrow aspiration samples whenever a bone marrow aspiration procedure is already being done for clinical purposes.

- donate saliva whenever blood draw is already being done for clinical purposes.

- allow the investigators to perform gene mutation profiling.

- allow the investigators to study gene mutation results.

- allow the investigators to perform pharmacogenetic profiling.

- allow the investigators to study pharmacogenetic profiles.

- allow the investigators to examine chromosome copy number variations.

- allow the investigators to examine genomic methylation.

- allow the investigators to quantify metabolomics/cytokines. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02435550
Study type Interventional
Source University of Florida
Contact
Status Terminated
Phase N/A
Start date June 26, 2015
Completion date October 1, 2019

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