Safety & Efficacy of Remote Ischemic Conditioning Combined EDAS on

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

Encephaloduroarteriosynangiosis (EDAS) is widely used as an indirect technique for treatment of moyamoya disease. Nevertheless, this indirect surgery tends to establish insufficient collateral circulation in most adult MMD patients. Nowadays, there is a lack of adjuvant therapies for improving collateral circulation induced by indirect revascularization. Remote ischemic conditioning (RIC) is a noninvasive approach protecting the brain by inflating and deflating blood-pressure cuff placed on the upper limbs. It has been confirmed to improve cerebral perfusion by promoting angiogenesis and arteriogenesis in ischemic animal brain. In addition, daily remote ischemic conditioning is a promising technique to ameliorate chronic cerebrovascular disease like intracranial atherosclerotic stenosis, small-vessel disease. Thus, this study aims to explore whether remote ischemic conditioning can improve the collateral circulation after indirect revascularization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04917003
Study type	Interventional
Source	Capital Medical University
Contact	Xunming Ji, PhD
Phone	861013120136877
Email	jixunming@vip.163.com
Status	Recruiting
Phase	N/A
Start date	June 15, 2021
Completion date	June 30, 2022

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Safety and Efficacy of Remote Ischemic Conditioning Combined EDAS on Ischemic Moyamoya Disease — RIC-IMD

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms