Morbid Obesity Clinical Trial
Official title:
Bariatric Procedures and Changes in Incretins and Gastric Emptying
The study evaluates the gastric emptying by scintigraphy in patients that had bariatric
surgery (RYGB of gastric sleeve) comparing patients with successful and unsuccessful weight
loss and in patients before and after the placement of a duodenal-jejunal bypass liner.
Additional, after bariatric surgery gut hormones that influence the gastric emptying rate
are determined.
Bariatric surgery reduces stomach volume and passage of foods through the gastrointestinal
tract is altered. The satiety level often increases, which is probably caused by gut
hormones. Patients response on different bariatric procedures varies widely and it is
difficult to predict which patient responds well. Possibly, patients who have successful
excess weight loss (EWL) two years after surgery have different gastric emptying rates
compared to unsuccessful patients.
Changes in gut hormones after implantation of a duodenal-jejunal bypass liner were
demonstrated in other studies. However, gastric emptying before and after placement of this
liner is unknown.
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