Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients

Morbid Obesity Clinical Trial

— RQ  

Official title:

Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01396460
• Other study ID #: NCT01231087
• Status: Completed
• Phase: N/A
• First received: July 15, 2011
• Last updated: September 7, 2012
• Start date: May 2011
• Est. completion date: July 2011

Study information

• Verified date: September 2012
• Source: Gastrocirurgia, Brazil
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Observational

Clinical Trial Summary

Through the values of respiratory quotient (RQ) it is possible to estimate the utilization of energy substrates by the body, or if there is a higher or lower fat oxidation. Experimental and clinical studies have shown that after Roux-en-Y Gastric Bypass (RYGBP) there is a decrease in the values of RQ, which may be associated with increased lipid oxidation in the postoperative period.

Diet Induced Thermogenesis (DIT) is an important part of Total Energy Expenditure. We would like to know how it functions among RYGBP patients.

The purpose of this study is to evaluate the RQ and DIT of patients in the post operative phase and compare the result with a control group consisting of morbid obese population.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: July 2011
• Est. primary completion date: June 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria (bariatric patients post-op)

• With more than 1 year after surgery

• Consent given to participate

Exclusion Criteria:

• Pregnant women

• Malnourished patients (anemia)

• Tiroid disorders without treatment

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Morbid Obesity
• Obesity, Morbid

Intervention

Other:
• breakfast (a chicken sandwich with juice)
patients received a breakfast after de initial measurement

Locations

Country	Name	City	State
Brazil	Gastrocirurgia de Brasilia	Brasilia	Distrito Federal

Sponsors (1)

Lead Sponsor	Collaborator
Gastrocirurgia, Brazil

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Diet Induced Thermogenesis	To examine the possible changes in the thermic effect of food, the patients received a standard meal. They then repeated the test 20 minutes after eating to obtain a reading of the metabolic rate by considering the DIT and RQ in the postprandial period. DIT was calculated as the difference between post prandial metabolic rate and RMR.	20min after standard meal	Yes