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NCT00852553 Clinical Trial

Neurohumoral Control of Intestinal Electrical and Mechanical Activity

Morbid Obesity Clinical Trial

Official title:
Neurohumoral Control of Intestinal Electrical and Mechanical Activity

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00852553
Other study ID # 200311379
Secondary ID 200311379-8
Status Completed
Phase N/A
First received February 26, 2009
Last updated May 24, 2017
Start date February 2003
Est. completion date February 2012

Study information
Verified date May 2017
Source University of California, Davis
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

A collaborative research project with Dr. Kathleen Keef (Department of Physiology, University of Nevada School of Medicine, Reno, Nevada) studying the role of putative neurotransmitters in human intestine.

Description:

Segments of intestine from patients undergoing elective gastric bypass for morbid obesity or resections for non-obstructive neoplasms at the UC Davis Medical Center will be used. Samples will be taken from tissue normally removed and sent to Pathology or discarded. Full thickness segments of intestine (10 mm x 1 mm) will be prepared for recording either intracellular electrical activity or mechanical contraction. The effects of putative non-adrenergic, non-cholinergic neurotransmitters (e.g., nitric oxide) will be studied. The source of the tissue will not be identified either directly or indirectly through identifiers associated with the measured responses.

Recruitment information / eligibility
Status Completed
Enrollment 45
Est. completion date February 2012
Est. primary completion date February 2012
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- All patients having elective bowel resection

Exclusion Criteria:

- Entire resected segment required for pathology

- Ischemic/necrotic disease

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Nevada School of Medicine Reno Nevada
United States University of California, Davis Medical Center Sacramento California

Sponsors (1)
Lead Sponsor Collaborator
University of California, Davis

Country where clinical trial is conducted

United States, 

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