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Neurohumoral Control of Intestinal Electrical and Mechanical Activity

Morbid Obesity Clinical Trial

Official title:
Neurohumoral Control of Intestinal Electrical and Mechanical Activity

Clinical Trial Summary

A collaborative research project with Dr. Kathleen Keef (Department of Physiology, University of Nevada School of Medicine, Reno, Nevada) studying the role of putative neurotransmitters in human intestine.

Clinical Trial Description

Segments of intestine from patients undergoing elective gastric bypass for morbid obesity or resections for non-obstructive neoplasms at the UC Davis Medical Center will be used. Samples will be taken from tissue normally removed and sent to Pathology or discarded. Full thickness segments of intestine (10 mm x 1 mm) will be prepared for recording either intracellular electrical activity or mechanical contraction. The effects of putative non-adrenergic, non-cholinergic neurotransmitters (e.g., nitric oxide) will be studied. The source of the tissue will not be identified either directly or indirectly through identifiers associated with the measured responses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00852553
Study type Observational
Source University of California, Davis
Contact
Status Completed
Phase N/A
Start date February 2003
Completion date February 2012
View Details
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