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Mitral Valve Disease clinical trials

View clinical trials related to Mitral Valve Disease.

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NCT ID: NCT03859102 Recruiting - Clinical trials for Coronary Artery Disease

Enhanced Recovery After Cardiac Surgery

ERAS
Start date: December 17, 2018
Phase: N/A
Study type: Interventional

Enhanced Recovery Protocols (ERPs or bundles) have been established in many surgical specialties (such as colon cancer and orthopaedic joint surgeries) for several years in hospitals worldwide. The principles of Enhanced Recovery Protocols are those of early mobilization and restoration of normal function as soon as possible after surgery. These principles are achieved by use of alternate pain control regimens and removing invasive lines and drains as soon as possible. The benefits of ERPs are improved patient experience, earlier return to normal function and reduced length of stay. Enhanced recovery protocols for cardiac surgery have been published by the Enhanced Recovery After Cardiac Surgery Society. The current study will investigate whether it is possible to utilise ERP bundles in the population of cardiac surgery patients at James Cook Hospital, with a view to rolling out a full ERP service. Secondary study outcomes will be patient-centred, including; pain scores, nausea and vomiting rates and time taken to return to normal function.

NCT ID: NCT03587688 Recruiting - Clinical trials for Mitral Valve Disease

Registry for Mitral Valve Surgery at Department of Cardiac Surgery University Hospital of Basel/ Switzerland

Start date: April 28, 2018
Phase:
Study type: Observational [Patient Registry]

A registry is installed to collect (pre-, intra- and postoperative) data on patients undergoing mitral valve surgery at the Department for Cardiac Surgery of Universitätsspital Basel/ Switzerland since 2009. Retrospective data (since 2009) as well as prospective data are included in this ongoing registry to analyse the development of mitral valve surgery at the Department of Cardiac Surgery University Hospital of Basel/ Switzerland.

NCT ID: NCT03574311 Recruiting - Clinical trials for Coronary Artery Disease

Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery

PREFER-CABG
Start date: October 2, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery. Half of the patients will receive ferric carboxymaltose and half of the patients physiological saline solution as placebo.

NCT ID: NCT03339115 Recruiting - Clinical trials for Mitral Regurgitation

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System

AHEAD
Start date: April 23, 2018
Phase: N/A
Study type: Interventional

This study will evaluate the safety of the Cardiovalve Transfemoral Mitral Valve System with its associated procedure, and observe the device performance in reducing mitral regurgitation. Data collected in this clinical study will include 30-day safety and performance, and long-term clinical outcomes over a follow-up of 2 years.

NCT ID: NCT03195595 Recruiting - Clinical trials for Mitral Valve Disease

Minimal Invasive Mitral Valve Replacement Versus Conventional Median Sternotomy Approach

Start date: April 1, 2020
Phase:
Study type: Observational

This is retrospective study that will be done in Cardiothoracic surgery department in Assuit university hospitals for one year duration aiming to compare minimal invasive technique to conventional median sternotomy for mitral valve surgery regarding early postoperative outcomes and pain

NCT ID: NCT02925819 Recruiting - Clinical trials for Mitral Valve Disease

Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery

MITRAGISTER
Start date: October 2016
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to collect in a prospective registry all cases of French patients undergoing an assessment for percutaneous treatment of mitral valve disease on a native valve or due to deterioration after surgical valve repair or replacement. In these patients, valvular surgery should be considered contra-indicated or at prohibitive risk. This registry will evaluate the morbidity and mortality up to 24 months for those patients with severe mitral valve disease who are not included in a clinical trial. The association of demographic, clinical, laboratory, echocardiographic variables and treatment options with morbidity and mortality will be evaluated by univariate and multivariate analyses.