Clinical Trials Logo

Clinical Trial Summary

This is a prospective observational study. Eligible women undergo ART treatment in our centre will be recruited for the study and each woman will only be included in the study once. Informed written consent will be obtained. Blood serum for hCG level is performed 14 days after the embryo transfer i.e. week 4. If the serum hCG level is >10IU/L, the women are considered pregnant and blood will be saved and checked for kisspeptin level, Another blood test is repeated 1 week later i.e. week 5. A transvaginal ultrasound and blood test will be performed 1 week later i.e. week 6 to confirm the fetal viability and the number of gestational sacs and locate the pregnancy. Blood for hCG and kisspeptin levels are checked at weeks, 4, 5 and 6. Ultrasound will be performed at gestational 8 weeks and 11 weeks. They will be referred for antenatal care when the pregnancy is confirmed on-going at 11 weeks. The purpose is to determine whether serum kisspeptin level in women who conceive in IVF is associated with an increased risk in first trimester miscarriage and compare with serum hCG level in the prediction of the first trimester miscarriage.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03940495
Study type Observational
Source ShangHai Ji Ai Genetics & IVF Institute
Contact
Status Completed
Phase
Start date May 1, 2019
Completion date August 1, 2020

See also
  Status Clinical Trial Phase
Recruiting NCT05969574 - Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
Enrolling by invitation NCT01689428 - Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases Phase 3
Completed NCT00194844 - Couples Miscarriage Healing Project:Randomized Trial Phase 1/Phase 2
Recruiting NCT05789940 - Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention N/A
Recruiting NCT03628625 - Letrozole Pretreatment With Misoprostol fInduction of Abortion In First-Trimester Missed Miscarriage Phase 2
Not yet recruiting NCT05557201 - Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors
Not yet recruiting NCT05579756 - Psychatric Impact of Miscarriage in Assiut University Hospital
Not yet recruiting NCT05039853 - Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task N/A
Recruiting NCT01223482 - A Study Looking at Women's Experiences After a Miscarriage N/A
Completed NCT04604366 - Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage Phase 2
Not yet recruiting NCT05094375 - Vaginal Misoprostol In Medical Treatment of First Trimester Missed Miscarriage N/A
Not yet recruiting NCT05088720 - Misoprostol for Management of Women With an Incomplete Miscarriage N/A
Not yet recruiting NCT05103098 - Sublingual Misoprostol In Medical Treatment of First Trimester Missed Miscarriage N/A
Not yet recruiting NCT05088707 - Sublingual Versus Vaginal Misoprostol In Medical Treatment of Second Trimestric Missed Miscarriage N/A
Recruiting NCT05304273 - Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages Phase 3
Not yet recruiting NCT05653414 - Interest of a Short Early Psychological Care in Women With Miscarriage N/A
Recruiting NCT03976544 - Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients Phase 4
Completed NCT01916928 - The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage N/A
Completed NCT04512820 - Treatment of Missed Miscarriage With TRUCLEAR Tissue Removal System, a Feasiblity Study N/A
Recruiting NCT05762770 - A Trial of Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception N/A