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Migraine clinical trials

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NCT ID: NCT06414044 Recruiting - Migraine Clinical Trials

Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients

STAR
Start date: May 9, 2024
Phase:
Study type: Observational

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of atogepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.

NCT ID: NCT06409845 Recruiting - Migraine Clinical Trials

Effectiveness and Tolerability of Eptinezumab

TACHIS
Start date: March 26, 2024
Phase:
Study type: Observational

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of eptinezumab as preventive migraine treatment in a cohort of episodic or chronic migraine patients.

NCT ID: NCT06409832 Recruiting - Migraine Clinical Trials

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment

RAISE
Start date: March 26, 2024
Phase:
Study type: Observational [Patient Registry]

The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.

NCT ID: NCT06401642 Not yet recruiting - Migraine Clinical Trials

Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications

Start date: May 2024
Phase: Phase 4
Study type: Interventional

Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.

NCT ID: NCT06372509 Recruiting - Clinical trials for Coronary Artery Disease

A Proteomic Analysis for Understanding the Link Between Migraine and Cardiovascular Disease

PMCD
Start date: April 3, 2024
Phase:
Study type: Observational

This is a multicenter, prospective observational study. Will be collecting data from 90 consecutive patients (aged 25- 60 years ) with and without migraine admitted at our Hospital. Primary aim of the study will be to assess the correlation between migraine and proteomic profiling of plasma and their possible correlation with known cardio and cerebrovascular disease and Cardiovascular (CV) risk factors.

NCT ID: NCT06361446 Recruiting - Migraine Clinical Trials

Zonisamide Versus Propranolol in Migraine

Start date: March 29, 2024
Phase: Phase 3
Study type: Interventional

Investigators aim to compare the effect of zonisamide versus propranolol in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved ≥ 50% reduction in the monthly headache days frequency compared to the baseline frequency

NCT ID: NCT06347497 Recruiting - Migraine Clinical Trials

Zonisamide Versus Topiramate in Migraine

Start date: April 1, 2024
Phase: Phase 3
Study type: Interventional

Investigators aim to compare the effect of zonisamide versus topiramate in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved ≥ 50% reduction in the monthly headache days frequency compared to the baseline frequency

NCT ID: NCT06345326 Recruiting - Migraine Clinical Trials

Greater Occipital Nerve Block Versus Pulse Radiofrequency in Migraine

GON-B/PRF
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the clinical efficacy of the repeated greater occipital nerve(GON) blokcs with GON pulse radiofreaquency (PRF)

NCT ID: NCT06334796 Completed - Stroke Clinical Trials

Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology

AIDEN
Start date: October 1, 2023
Phase: Early Phase 1
Study type: Interventional

This study examines the use of an AI-powered virtual assistant for quickly identifying and handling neurological emergencies, particularly in places with limited medical resources. The research aimed to check if this AI tool is safe and accurate enough to move on to more advanced testing stages. In a first-of-its-kind trial, the virtual assistant was tested with patients having urgent neurological issues. Neurologists first reviewed the AI's recommendations using clinical records and then assessed its performance directly with patients. The findings were as follows: neurologists agreed with the AI's decisions nearly all the time, and the AI outperformed earlier versions of Chat GPT in every tested aspect. Patients and doctors found the AI to be highly effective, rating it as excellent or very good in most cases. This suggests the AI could significantly enhance how quickly and accurately neurological emergencies are dealt with, although further trials are needed before it can be widely used.

NCT ID: NCT06334237 Not yet recruiting - Migraine Clinical Trials

Psychosomatic Factors Influencing the Efficacy of Holistic Care for Migraine

Start date: April 15, 2024
Phase:
Study type: Observational

This research project aims at exploring the psychosomatic factors that influence and moderate the efficacy of holistic care and personalized treatment for migraine patients. It is a prospective longitudinal observational study. The project's goal is to understand how physical, psychological, spiritual, and social factors affect the care and treatment outcomes for migraineurs. The study will include participants aged 18 to 65, who meet the International Headache Society's criteria for migraines. It will utilize a range of methodologies including questionnaires, interviews, and medical records to collect data on various factors like lifestyle, psychological state, and social support. The project will assess the effectiveness of treatments, compliance, and other outcomes such as emotional and sleep conditions.