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Clinical Trial Summary

With current antiretroviral therapy, people living with HIV reach virological suppression faster, which in turn leads to a higher life expectancy. Nevertheless, this improved survival rate is not free of other comorbidities, such as metabolic syndrome, characterized by a decrease in glucose tolerance and an increase in insulin resistance. Berberine is an alkaloid that has proven beneficial effects on both glucose tolerance and insulin resistance, but has not been tested in people living with HIV under virological suppression. We hypothesize that berberine will improve inflammatory markers and metabolic profile in this population without significant interactions nor adverse effects.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04860063
Study type Interventional
Source Hospital Civil de Guadalajara
Contact
Status Not yet recruiting
Phase Phase 3
Start date April 2021
Completion date July 2022

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