Effects of Water-Based Exercise in Women With Metabolic Syndrome

Metabolic Syndrome Clinical Trial

Official title:

Effects of Water-Based Aerobic Training, Resistance Training and Concurrent Training in Women With Metabolic Syndrome: A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03210597
• Other study ID #: CEP UFRGS 1.499.603
• Status: Completed
• Phase: N/A
• Start date: August 1, 2016
• Est. completion date: October 10, 2018

Study information

• Verified date: October 2018
• Source: Federal University of Rio Grande do Sul
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of the present study was to compare the neuromuscular, cardiorespiratory and metabolic effects of 12 weeks of aerobic training, strength training and combined training in the aquatic environment in women with MS. For this purpose, 51 postmenopausal, sedentary and MS women were randomly divided into three intervention groups: hydro-aerobic (HA, n = 18, 63.77 ± 5.03 years), hydro-power (HF, n = 16, 61.01 ± 4.93 years) and hydro-combined (HC; n = 17; 60.52 ± 6.91). A subsample participated in eight weeks without physical exercise to characterize a control period. The three intervention groups performed two weekly sessions of 60 minutes for 12 weeks. Before and after the training period, blood tests, muscle strength tests, cardiorespiratory evaluation, functional tests and a questionnaire were performed. For statistical analysis, the Generalized Estimates Equations (GEE) model was used, using the "group" and the "time" as factors. The Bonferroni post hoc was used to locate the differences and the significance index adopted was α = 0.05.

Description:

Water-based exercise as a mode of aquatic exercise has been highlighted in the scientific literature. Research on different models of training, aerobic, muscle strength and combined (aerobic and muscle strength), have already demonstrated their beneficial effects on different physical abilities. Recent studies indicate benefits of water-based exercise for the population with metabolic diseases such as hypertension, type 2 diabetes, dyslipidemias and obesity. However, for subjects with metabolic syndrome (MS) there are few studies that investigated which training model in the aquatic environment could generate physical and metabolic improvements.

This study is characterized as a randomized clinical trial, which treated three intervention groups with physical exercise programs. A subsample participated in a period of eight weeks without physical exercise to characterize a control period. The subjects in this subsample were later randomized into the intervention groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 51
• Est. completion date: October 10, 2018
• Est. primary completion date: December 28, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Postmenopausal;

• Sedentary;

• Presented at least three positive components within the five possible to characterize the metabolic syndrome.

Exclusion Criteria:

• Smokers.

Related Conditions & MeSH terms

• Metabolic Syndrome
• Metabolic Syndrome X
• Syndrome

Intervention

Other:
• Exercise
The subjects performed training in aquatic environment

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of Rio Grande do Sul

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Systolic and diastolic blood pressure	mmHg	12 weeks
Secondary	Strength tests: Maximum dynamic muscle strength	One repetition test: how many kilograms the subject is able to withstand on a repetition of elbow flexion and knee extension exercise	12 weeks
Secondary	EMG test	Maximum isometric amplitude of the electromyographic signal of the vastus lateralis and rectus femoris muscles	12 weeks
Secondary	Time Up and go test	How long (in seconds) the subject needs to lift from a chair, walk 2.44 meters, and sit in a chair again	12 weeks
Secondary	Sit and Stand test	How often in 30 seconds the subject is able to get up and sit on a chair.	12 weeks
Secondary	Triglyceride levels	blood test: mg/dl	12 weeks
Secondary	HDL cholesterol levels	blood test: mg/dl	12 weeks
Secondary	Fasting blood glucose levels	blood test: mg/dl	12 weeks
Secondary	Waist circumference	centimeters	12 weeks