Metabolic Syndrome Clinical Trial
Official title:
Prevalence of Lipodystrophy Syndrome and Secondary Metabolic Syndrome in HIV-infected Patients
To evaluate the prevalence of lipodystrophy syndrome in patients receiving currently available antiretroviral drugs, and the prevalence of associated metabolic syndrome in HIV-infected patients with a previous diagnosis of lipodystrophy syndrome, according to the severity of fat accumulation and antiretroviral drug use.
Cross-sectional evaluation of two groups of patients:
- patients receiving currently available drugs, in order to determine the changes in fat
accumulation by successive dual X-ray absorptiometry (DXA) determinations
- patients with previous lipodystrophy syndrome, as evaluated by questionnaire (HOPS) and
total body dual X-ray absorptiometry (DXA), in order to determine the prevalence of
hypertension, low high density lipoprotein (HDL)-cholesterol, glucose disturbance
(insulin resistance or diabetes), fat accumulation (waist circumference) and
hypertriglyceridemia.
The prevalence of Metabolic syndrome will be evaluated according to the different definitions
(IDF, NCEP-ATP III, WHO).
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