Metabolic Syndrome Clinical Trial
Official title:
Effects of Ginsenoside Supplementation on Insulin Resistance and Cardiometabolic Risk Factors in Men With Metabolic Syndrome: a Randomized Controlled Trial.
Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters
such as cholesterol, blood pressure and glucose.
Randomized Control Trial.
Methods : A randomized, double-blind, placebo-controlled, single-center study in 60 subjects
who are not taking drugs that could affect metabolic and vascular function. Subjects will be
randomized into a Korean red ginseng (3.0g/d) group or placebo group for a 4-week study.
We will collect anthropometric measurements, blood for laboratory testing, inflammatory
marker, hormones and mitochondrial DNA copy number.
Subject : Older than 40 years of age, presented with metabolic syndrome. Subjects were
excluded if they were taking drugs that could affect metabolic and vascular function,
including BP control drug, anti-diabetic drugs and lipid-lowering drugs.
Measurement : We will collect anthropometric measurements and blood for laboratory testing
at the initial(week 0) and final (week 4)visits. Serum levels of blood glucose, insulin,
total cholesterol, HDL-cholesterol,triglyceride, and DNA copy number of mitochondria.
;
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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