Clinical Trials Logo
  1. Home
  2. Metabolic Syndrome X
  3. NCT03019796

Exercise Training Effects on Metabolic Syndrome: Interactions With Medication — METSYND  

Metabolic Syndrome X Clinical Trial

Official title:
Effects of Exercise Training as a Non-pharmacological Treatment for Metabolic Syndrome and Its Interactions With Subjects Habitual Medications.

Clinical Trial Summary

To analyze the effects of different exercise training modalities (continuous, intervallic, and resistance training) on cardiorespiratory and metabolic fitness of metabolic syndrome patients when this training interacts with their habitual medication.

Clinical Trial Description

Objective: The purpose is to study in a group of adults with metabolic syndrome and obesity, the effects of different modalities of exercise training on cardiorespiratory and metabolic fitness. The main objective is to weight the effects of exercise training separately and in conjunction with the subject's habitual pharmacological treatment to identify the best combination of drug and exercise. Methods and design: Randomized, pretest-posttest control group experimental design. Project developed in a single center with the collaboration of the regional public health system. Subjects: Will be referred by their primary care physicians to our study unit. Up to 40 subjects all of them with metabolic syndrome will be recruited (at least 20% women). Measurements: 1. Specifically, the investigators, will study cardiovascular adaptations that increase, i) maximal aerobic capacity measured by VO2max, ii) anaerobic and respiratory compensation point ventilatory thresholds, iii) arterial stiffness, measured by pulse wave velocity (SphygmoCor System), v) central and peripheral blood pressure, and iv) biological markers of endothelial dysfunction using reactive hyperemia with a laser Doppler fluxmeter in central and peripheral blood vessels. 2. The metabolic adaptations under study will include, i) insulin sensitivity by HOMA-IR, ii) fat oxidation by indirect calorimetry ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03019796
Study type Interventional
Source University of Castilla-La Mancha
Contact
Status Completed
Phase Early Phase 1
Start date July 2015
Completion date August 2020
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT02702375 - Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases N/A
Completed NCT02918422 - Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption N/A
Completed NCT02649348 - Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome N/A
Completed NCT02356952 - Effect of a Low Glycemic Index on Metabolic Syndrome N/A
Completed NCT02459691 - Culturally-adapted Diabetes Prevention Lifestyle Intervention for Latinos (E-LITE Latinos) N/A
Completed NCT02337933 - Effect of Ursolic Acid Administration on Insulin Sensitivity and Metabolic Syndrome Phase 2
Completed NCT02402985 - Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics N/A
Completed NCT01694056 - Soy Protein Intake and the Metabolic Syndrome N/A
Completed NCT00344903 - Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort N/A
Recruiting NCT00408824 - Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study) N/A
Completed NCT00395486 - ROMEO (Rosuvastatin in Metabolic syndrOme) Phase 4
Completed NCT00362908 - Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome N/A
Completed NCT00140816 - Dairy Products and Metabolic Effects (Norwegian Part) N/A
Completed NCT00455325 - Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS) Phase 2
Completed NCT00166036 - Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells Phase 2
Completed NCT00101517 - Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease N/A
Recruiting NCT00177892 - Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress N/A
Completed NCT00073775 - Epidemiology of Stress and the Metabolic Syndrome N/A
Completed NCT00074451 - Genomewide Search for Loci Underlying Metabolic Syndrome
Completed NCT00200993 - Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE I) Phase 2