Meniscus Lesion Clinical Trial
Official title:
Early Viscosupplementation After Partial Meniscectomy: a Double Blind, Placebo Controlled Randomized Trial
The rational of intra-articular viscosupplementation is based on both the biological and
mechanical properties of HA, which exerts positive effects on the modulation of the entire
joint environment.
The aim of the present double blind controlled study was to evaluate the effects in terms of
pain control and functional recovery provided by a single intra-operative injection of HA
performed at the end of arthroscopic partial meniscectomy.
Patients included in this trial were randomized in two treatment groups: the first one
received a single injection of HA (Hymovis 24 mg/3ml, Fidia Farmaceutici Spa, Padova, Italy)
at the end of the arthroscopic meniscectomy, whereas the second group was treated by surgery
alone.
All patients were evaluated basally, at 15, 30, 60, and 180 days after surgery by the
following evaluation tools: IKDC (International Knee Documentation Committee) subjective, VAS
(Visual Analogue Score) for pain, EQ-VAS for general Health Status, KOOS (Knee Injury and
Osteoarthritis Outcome Score) and Tegner score. Furthermore, during the basal evaluation and
at each follow-up visit up to 2 months, active and passive Range of Motion (ROM) of both the
operated and contralateral knee were documented; also in addition, the trans-patellar
circumference of both knees was registered to assess the trend of knee swelling over time.
n/a
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