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Memory clinical trials

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NCT ID: NCT06074172 Completed - Memory Clinical Trials

The Effect of Cannabidiol in Learning and Memory of Adults

Start date: March 14, 2020
Phase: Phase 2
Study type: Interventional

The main objectives of this study were to test if a singular dose of Cannabidiol (1) enhances the learning and memory of healthy human subjects, (2) test if Cannabidiol has negative effects on Retroactive and Proactive Interference during learning, (3) and test if demographic factors will influence CBD's modulation of human learning and memory.

NCT ID: NCT06047899 Completed - Memory Clinical Trials

Influence of Luteolin for Two Weeks on Memory in Healthy Subjects

LuMus2-2023
Start date: November 28, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effect of the dietary supplement luteolin in healthy people. The main question it aims to answer is: Does luteolin have an influence on memory functions? Participants will go trough two treatment phases. In one phase they will take 250mg luteolin twice daily for two weeks. In the other phase they will take a placebo twice daily for two weeks. A placebo is a look-alike substance that contains no active drug. At the start and end of teach treatment phase, participants will undergo different memory testing exercises in our research facility.

NCT ID: NCT05907707 Completed - Aging Clinical Trials

Effects of Gamma-tACS on Memory and Sleep

Start date: June 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to investigate the feasibility and efficacy of non-invasive transcranial alternating current stimulation (tACS) at gamma frequency in enhancing memory recall and modulating sleep network dynamics measured by at-home electroencephalography (EEG) in healthy elderly people. Eligible participants will first collect sleep EEG at home for one night to acclimate to the data collection during sleep. Participants are then randomized into first undergoing either tACS at gamma band frequencies (i.e. 40Hz) or tACS at a control frequency (i.e. 21Hz). Stimulation is administered in the lab during a cognitive testing battery that includes memorizing items. After a night of sleep with EEG at home, participants return to the lab the following day to measure memory recall. Recall is performed again after five days. This sequence of encoding during stimulation in the lab, sleep EEG at home for one night, and recall is then repeated for the other stimulation condition about a week later. Participants are wearing an actigraphy wristband throughout the study period.

NCT ID: NCT04854811 Completed - Clinical trials for Cerebrovascular Disorders

Roflumilast to Treat Cognitive Sequela After Stroke

ROSTMEMA
Start date: July 7, 2021
Phase: Phase 2
Study type: Interventional

The aim of the current project is to validate the effects of chronic rolflumilast treatment (12 weeks) on cognitive functions (i.e. episodic memory) by means of behavioral tasks, in people suffering from cognitive impairments at least 1 year after stroke. Secondarily, the effects of roflumilast on daily activities and well-being will be assessed.

NCT ID: NCT04584138 Completed - Alzheimer's Disease Clinical Trials

Autobiographical Memory

EMAM
Start date: April 15, 2021
Phase:
Study type: Observational

This study aims at the assessment of eye movement during autobiographical retrieval (i.e., retrieval of personal memories) in patients with Alzheimer's Disease.

NCT ID: NCT04330677 Completed - Memory Clinical Trials

Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin

ESMory
Start date: September 18, 2016
Phase: Phase 1
Study type: Interventional

The study aims to examine a behavioral and neural framework for understanding the sex-specific effects of the neuropeptide oxytocin (OXT). Using hormonal, behavioral and neuroimaging readouts, it is planned to explore the interplay of OXT and estradiol as a potential mechanism mediating sexual dimorphic effects.

NCT ID: NCT04025255 Completed - Cognitive Function Clinical Trials

The Memory and Cognitive Performance Study

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The primary purpose of this study is to evaluate the impact of a novel, neuro-protective and neuro-restorative dietary supplement (Braini®) on standardized memory and cognitive performance parameters. The principal active ingredients in the Braini® supplement have been commercially-available since at least 2015 or have achieved FDA new dietary ingredient notification (NDIN) in 2018, with no adverse events reported to the FDA. A 28-day randomized, double-blinded, placebo-controlled dietary supplement study will be conducted with a cohort of younger and a cohort of colder adults to achieve the purpose of this study. The research team hypothesizes that Braini® will improve standardized performance scores measured by CNS Vital Signs standard memory and cognitive performance assays more effectively than placebo.

NCT ID: NCT03985917 Completed - Depression Clinical Trials

Singing Groups for Seniors: Well-Being, Cognitive Function and Health

Sing4Health
Start date: December 5, 2018
Phase: N/A
Study type: Interventional

The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.

NCT ID: NCT03974399 Completed - Memory Clinical Trials

BDNF Levels After Bacopa

Start date: May 30, 2019
Phase: N/A
Study type: Interventional

Brain-derived neurotrophic factor (BDNF) is a well-known neurotrophic factor important for learning, memory, and synaptogenesis. Healthy activities such as exercise are believed to raise BDNF, while stress is associated with lower BDNF. What is not well understood is if there are certain supplements that may raise BDNF over time. Bacopa monnieri is well characterized nutraceutical. Animal and pre-clinical data support multiple beneficial mechanisms, including raising BDNF and increasing synaptogenesis. Additionally, small studies have shown Bacopa enhances cognition and improves mood. We would like to investigate if BDNF level changes in people after starting Bacopa.

NCT ID: NCT03763409 Completed - Memory Clinical Trials

Losartan and Emotional Memory

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

This study explores the effects of single-dose losartan (50mg) versus identical placebo capsule on emotional memory and learning in healthy volunteers.