Mastectomy Clinical Trial
Official title:
Efficacy of Combination of Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post Mastectomy Complex Regional Pain Syndrome, Randomized Controlled Study.
The aim of this study is to evaluate the efficacy of the combination of Ultra Sound (US) guided radiofrequency stellate ganglion block (SGB) and radiofrequency Thoracic Paravertebral block (TPVB) comparing to US-guided SGB or TPVB alone on the post-mastectomy pain syndrome (PMPS).
Breast cancer is the most common malignancy among females, with an incidence of about 2.1 million women each year. It is the most common cause of cancer-related deaths among women. Modified Radical Mastectomy (MRM) is one of the main surgical treatments for breast cancer. It accounts for 31% of all breast surgery cases. Nearly 40-60% of breast surgery patients experience severe acute postoperative pain, with severe pain persisting for 6-12 months in almost 20-50% of patients (post-mastectomy pain syndrome. Complex regional pain syndrome (CRPS) is a clinical diagnosis with a highly variable presentation and prognosis. CRPS type I, previously known as reflex sympathetic dystrophy (RSD), is not associated with direct nerve injury. CRPS type II, or causalgia, is associated with direct injury of a specific nerve, often from surgical intervention or trauma. Symptoms include severe pain, sensitivity to light touch, burning, sweating, skin discoloration, edema, temperature changes, loss of motor function, and decreased range of motion of the affected limb. The mechanism of CRPS is not fully understood with central and peripheral sensitization involved. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03618433 -
KİNECT® - Video Games Based Physiotherapy Programme in Patients With Breast Cancer Surgery
|
N/A | |
| Terminated |
NCT05395936 -
Mastectomy Flap Temperature Study
|
N/A | |
| Recruiting |
NCT03757793 -
Near-infrared Spectroscopy for Monitoring Tissue Oxygenation in Breast Reconstruction
|
||
| Completed |
NCT01781299 -
Acellular Dermal Matrix in Tissue Expander Breast Reconstruction: A Prospective, Randomized, Clinical Trial Comparing SurgiMend PRS and AlloDerm RTU
|
Phase 4 | |
| Completed |
NCT01176786 -
Reusable Versus Disposable Draping System in Breast Reconstruction Surgery
|
N/A | |
| Terminated |
NCT00616824 -
The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction
|
Phase 4 | |
| Recruiting |
NCT05975359 -
Assessment of the Interi Manifold in Implant-Based Breast Reconstruction
|
N/A | |
| Withdrawn |
NCT03135392 -
Sensation After Nipple Sparing Mastectomy and Breast Reconstruction With or Without Neurotized Free Tissue Transfer
|
N/A | |
| Recruiting |
NCT01217593 -
Ultrasound vs. Predetermined Distance Techniques for Paravertebral Nerve Block in Patients Having Breast Surgery
|
N/A | |
| Completed |
NCT01231204 -
Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks
|
Phase 4 | |
| Recruiting |
NCT05069805 -
Comparison of Erector Spinae Plane Block and Pectoral Nerve Block for Acute and Chronic Pain in Mastectomies
|
N/A | |
| Completed |
NCT01687348 -
Lidocaine Pharmacokinetics During Tumescent Infiltrative Anaesthesia for Mastectomy
|
Phase 3 | |
| Completed |
NCT00555503 -
Registry of Mastectomy for Breast Cancer Risk Reduction
|
N/A | |
| Recruiting |
NCT03598712 -
Local Compression Seroma DIminution Objective (CLODIS)
|
Phase 3 | |
| Not yet recruiting |
NCT04457167 -
Mastectomy With Retention of the Nipple-areola Complex, Robot-assisted or Not, and / or Immediate or Seconday Reconstruction by Latissimus Dorsi Flap, Robot-assisted or Not.
|
N/A | |
| Recruiting |
NCT05494502 -
Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients
|
N/A | |
| Recruiting |
NCT02894021 -
PREvention of Post-mastectomy LYMphoceles by PAdding
|
N/A | |
| Recruiting |
NCT04891510 -
A Comparative Analysis of REVOLVE, LipoGrafter, and the Standard Decantation Technique in Autologous Fat Grafting During Breast Surgery
|
N/A | |
| Enrolling by invitation |
NCT05658367 -
Effect of Aromatherapy Massage on Pain and Anxiety After Mastectomy
|
N/A | |
| Terminated |
NCT05126615 -
Contribution of Auriculotherapy in the Management of Mastectomy With Immediate Reconstruction by Latissimus Dorsi Flap (ATMAGD)
|
N/A |