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Clinical Trial Summary

This is a prospective, multicenter phase II trial designed to evaluate the safety and activity of the combination of Bendamustine, Lenalidomide and Rituximab (R2-B) in patients with first relapsed/refractory mantle cell lymphoma (MCL) and the efficacy and safety of a maintenance treatment with Lenalidomide for 18 months from the end of R2-B (from month 7 to 24) for those responding to the induction.


Clinical Trial Description

This is a phase II study, non randomized, multicenter. Patients with MCL refractory to front line therapy or in first relapse will be enrolled.

The study includes an induction phase, a consolidation phase, a maintenance phase and a follow up phase. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01737177
Study type Interventional
Source Fondazione Italiana Linfomi ONLUS
Contact
Status Completed
Phase Phase 2
Start date July 31, 2012
Completion date February 2, 2017

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