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Clinical Trial Summary

This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic malignancies.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04904588
Study type Interventional
Source Center for International Blood and Marrow Transplant Research
Contact Sarah Smith, RN, BSN
Phone 763-406-5397
Email ssmith23@nmdp.org
Status Recruiting
Phase Phase 2
Start date September 30, 2021
Completion date July 2024

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