Lung Injury Clinical Trial
Official title:
Effect of Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery
During cardiac surgery with cardiopulmonary bypass , pulmonary dysfunction remains to be a
problem complicating the postoperative course of the patients.Remote ischemic
preconditioning(RIPC) with transient upper limb ischemia/reperfusion is a novel, simple,
cost-free,non-pharmacological and non-invasive strategy.Recent several trials suggested that
RIPC could provide pulmonary protection by reducing serum biomarkers,however,whether the
RIPC can improve the clinical outcomes in patients undergoing on-pump cardiac surgery,is
still uncertain.
The study hypothesis is: remote ischemic preconditioning will provide lung-protective effect
and improve clinical outcomes in patients undergoing cardic surgery.
Remote ischemic preconditioning (RIPC) protocol will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood pressure cuff inflated to a pressure 200mmHg ;
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