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Clinical Trial Summary

During cardiac surgery with cardiopulmonary bypass , pulmonary dysfunction remains to be a problem complicating the postoperative course of the patients.Remote ischemic preconditioning(RIPC) with transient upper limb ischemia/reperfusion is a novel, simple, cost-free,non-pharmacological and non-invasive strategy.Recent several trials suggested that RIPC could provide pulmonary protection by reducing serum biomarkers,however,whether the RIPC can improve the clinical outcomes in patients undergoing on-pump cardiac surgery,is still uncertain.

The study hypothesis is: remote ischemic preconditioning will provide lung-protective effect and improve clinical outcomes in patients undergoing cardic surgery.


Clinical Trial Description

Remote ischemic preconditioning (RIPC) protocol will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood pressure cuff inflated to a pressure 200mmHg ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03016182
Study type Interventional
Source Xuzhou Medical University
Contact Liu Su, M.D/Ph.D
Phone +86-18118309692
Email xyfymzk@163.com
Status Recruiting
Phase N/A
Start date February 7, 2017
Completion date February 2018

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