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Lung Cancer clinical trials

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NCT ID: NCT03207594 Active, not recruiting - Breast Cancer Clinical Trials

Improving Evidence-Based Care for Cancer Patients

Start date: September 1, 2016
Phase:
Study type: Observational

The purpose of this study is to improve cancer care and the delivery of cancer care. Researchers are interested in studying patient reported information and examining how different factors may impact cancer care.

NCT ID: NCT03201146 Recruiting - Lung Cancer Clinical Trials

Apatinib Combine With Platinum‐Based Doublet Chemotherapy for First-line Treatment of Advanced NSCLC

Start date: June 27, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and clinical activity of Apatinib in combination with AP(Pemetrexed/Carboplatin) or AC(Pemetrexed/Carboplatin) as first-line chemotherapy in subjects with advanced EGFR wild type non-squamous non-small cell lung cancer(NSCLC).

NCT ID: NCT03199586 Completed - Breast Cancer Clinical Trials

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Start date: December 21, 2017
Phase: Phase 1
Study type: Interventional

Phase 1 A: First-in-human phase 1 study to determine safety of NP-G2-044 when given orally on a daily X 28 days followed by a 14 day rest period.

NCT ID: NCT03198468 Completed - Lung Cancer Clinical Trials

Vapor Ablation for Localized Cancer Lesions of the Lung (VAPORIZE)

VAPORIZE
Start date: November 21, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, single-arm, multi-center, pilot trial of Bronchoscopic Thermal Vapor Ablation for Lung Cancer (BTVA-C) in patients with primary lung cancer or metastatic cancer in the lung. Patients who have consented to participate in this study (enrolled) will be subject to eligibility screening and baseline assessments, prior to undergoing the BTVA-C procedure. Only patients that meet all of inclusion criteria and none of the exclusion criteria will receive vapor ablation treatment. Patients will receive BTVA-C treatment followed by standard-of-practice surgical resection.

NCT ID: NCT03198052 Recruiting - Cancer Clinical Trials

GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers

Start date: July 1, 2017
Phase: Phase 1
Study type: Interventional

The third generation of CAR-T cells that target GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR have been constructed respectively and their anti-cancer function has been verified by multiple in vitro and in vivo studies.Clinical studies will be performed to test the anti-cancer function of the these individual or combination of the CAR-T cells for immunotherapy of human cancer patients with GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR expressions. In this phase I study, the safety, tolerance, and preliminary efficacy of the GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR -CAR-T cell immunotherapy on human cancers will firstly be tested.

NCT ID: NCT03195491 Completed - Lung Cancer Clinical Trials

A Study of Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Second-Line Nivolumab Monotherapy in Asia

CheckMate870
Start date: December 25, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the safety of patients in Asia with Non-Small Cell Lung Cancer (NSCLC)who are treated with Nivolumab monotherapy as a second line or third line treatment.

NCT ID: NCT03192501 Recruiting - Cancer Clinical Trials

iCAGES-guided Precision Therapy for Cancers in Contrast to Standard Care or IHC-guided Theray

Start date: July 1, 2017
Phase:
Study type: Observational

This study prospectively evaluates whether the use of iCAGES (integrated CAncer GEnome Score) tool in guiding the treatment of advanced cancers is superior to current standard care or IHC-guided therapy in progress free survival (PFS),overall survival (OS),and improvement of life quality.

NCT ID: NCT03189277 Not yet recruiting - Lung Cancer Clinical Trials

A Hospital Based Survey on Lung Cancer Related-pain in Northern China

Start date: June 2017
Phase: N/A
Study type: Observational

This cross-sectional study, utilizing two sets of questionaire designed for patients and physicians respectively, aims at the epidemiology, the clinical features, and the current status of evaluation and management of lung cancer related pain in 20 participating hospitals in Northern China.

NCT ID: NCT03185754 Recruiting - Lung Cancer Clinical Trials

Comparison of Sublobar Resection and Lobectomy to Treat Lung Cancer

Start date: June 12, 2013
Phase: N/A
Study type: Interventional

A multi-center prospective randomized trial in Taiwan to investigate whether sublobar resection, as compared to lobectomy, can offer equivalent clinical results to treat early non-small cell lung cancer.

NCT ID: NCT03183232 Completed - Lung Cancer Clinical Trials

Safety and Efficiency of γδ T Cell Against Lung Cancer

Start date: June 15, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

In this study, effects of γδT cells on human Lung Cancer in combination with tumor reducing surgery, for example, cryosurgery going to be investigated