Clinical Trials Logo

Clinical Trial Summary

The objective of this study is to determine if surgery is superior to non-operative care for sciatica caused by a lumbar disc herniation. This study will include patients that have had severe sciatica for greater than 4 months which reflects the wait time of the Canadian health care system. This study is an opportunity to make an important contribution to medical science as there is no "top tier" evidence for or against this highly prevalent surgery. Although there have been several recent randomized trials in the field, all have been marred by a large number of patient crossing over from non-operative to operative treatment. Due to the wait for spine surgery, the Canadian system has a built-in delay that prevents such a cross over of patients. This study capitalizes on this unique opportunity to perform a high caliber surgical trial. Patients consenting to be in the study will be randomly assigned to expedited surgery within three weeks or standardized non-operative care while they wait on the surgeons list for consultation and then surgery (minimum wait of 9 months). The study will assess pain, function, quality of life, satisfaction, and work status to determine if one treatment is superior.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01335646
Study type Interventional
Source The London Spine Centre
Contact
Status Completed
Phase N/A
Start date March 21, 2010
Completion date August 2018

See also
  Status Clinical Trial Phase
Terminated NCT05047679 - The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy N/A
Withdrawn NCT03543033 - Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes N/A
Recruiting NCT06076408 - Effects of SNAGS With and Without Pilates in Lumbar Disc Bulge Patients N/A
Completed NCT03133845 - Shaping Anesthetic Techniques to Reduce Post-operative Delirium N/A
Completed NCT06087107 - Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa In Patients Of Lumbar Radiculopathy N/A
Completed NCT04852900 - Different Dosage of Decompression Therapy on Symptoms of Lumbar Radiculopathy N/A
Terminated NCT05022251 - Identifying Pain Generators and Potentiators of Residual Complaints Following Lumbar Discectomy
Recruiting NCT04212949 - The Effect of Transcranial Magnetic Stimulation Therapy in Patients With Lumbar Radiculopathy N/A
Terminated NCT03952377 - Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain Phase 1/Phase 2
Recruiting NCT06339931 - Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy. N/A
Recruiting NCT04540068 - Prediction of TEI Success in Sciatica
Recruiting NCT05922228 - Effects of Neural Flossing and PNF on Lumbar Radiculopathy N/A
Recruiting NCT05953727 - Low Level LASER Therapy With and Without Proprioceptive Stimulation Among Discogenic Lumbar Radiculopathy Patients N/A
Completed NCT05449288 - Urdu Version Of Modified Oswestry Low Back Pain Scale; A Reliability And Validity Study
Completed NCT05874427 - Comparison Between the Imaging Consent Form and the Existing Narrative Consent Form N/A
Terminated NCT01443819 - Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy Phase 3
Recruiting NCT05535010 - The Effect of the Presence of Active Trigger Points in the Muscles Innervated by the Affected Nerve Roots on the Treatment Results of Transforaminal Epidural Steroid Injection in Patients With Lumbar Radiculopathy. N/A
Recruiting NCT06154005 - OsteoAdapt SP Advanced Bone Graft Feasibility Study - Transforaminal Interbody Lumbar Fusion Phase 1/Phase 2
Completed NCT04674917 - Effects of Decompression in Patient With Acute vs Chronic Lumbar Radiculopathy N/A
Not yet recruiting NCT06296303 - Effect of Pulsed Magnetic Therapy Versus Phonophoresis in Discogenic Lumbar Radiculopathy Patients N/A