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NCT06080308 Clinical Trial

Liver Ischemia-reperfusion Injury and Clinical Data Analysis

Liver Injury Clinical Trial

Official title:
Research on the Molecular Mechanisms of Liver Ischemia-reperfusion Injury and Clinical Data Analysis: an Observational Study

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06080308
Other study ID # TJ-IRB20230940
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 10, 2023
Est. completion date September 30, 2024

Study information
Verified date April 2024
Source Tongji Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Searching for new targets for the diagnosis and treatment of liver ischemia-reperfusion injury.

Description:

Through the analysis of serological data during liver resection elective surgery with hepatic pedicle occlusion and reperfusion, as well as the analysis of patient-related data, we aim to identify key target points that affect reperfusion injury and explore their underlying mechanisms.

Recruitment information / eligibility
Status Recruiting
Enrollment 270
Est. completion date September 30, 2024
Est. primary completion date December 20, 2023
Accepts healthy volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: 1. Willingness to participate in the study and has signed an informed consent form. 2) Age = 18 years and = 70 years. 3) ASA classification = III. 4) Criteria for liver ischemia-reperfusion injury patients: patients undergoing elective liver resection surgery with hepatic pedicle occlusion and reperfusion during the procedure. Exclusion Criteria: 1) Patients with adverse events during surgery. 2) Patients in the end stage of disease with liver failure. 3) Liver tumor metastasis with concomitant severe heart failure or chronic renal insufficiency, etc. 4) Deemed unsuitable for participation in the study based on the judgment of the researchers. -

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• No intervention
No intervention

Locations
Country Name City State
China Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei

Sponsors (1)
Lead Sponsor Collaborator
Qin Zhang

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Length of hospital stay Length of hospital stay 7days
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