Swiss Primary Biliary Cholangitis Cohort Study

Status Recruiting

Clinical Trial Summary

Research project in which biological material is sampled and health-related medical data is collected. In addition, already existing health-related medical data are used for further research. Coded data are used.

Clinical Trial Description

Enrolment visit and one follow-up visit at least once a year are planned. Whole blood is collected for biobanking once a year. Optionally, if available and collected during normal clinical procedures, liver fragments are obtained. To collect high quality prospective data on a rare disease in order to elucidate epidemiology, natural history, response to treatment and outcome. In addition, the biobank allows addressing specific scientific issues on a variety of open questions. The cohort will provide a platform for carrying out scientific research projects on PBC. In addition, the cohort will allow collaboration with reference networks on PBC abroad. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03146910
Study type	Observational [Patient Registry]
Source	Fondazione Epatocentro Ticino
Contact	Benedetta Terziroli Beretta-Piccoli, MD
Phone	+41919608503
Email	benedetta.terziroli@hin.ch
Status	Recruiting
Phase
Start date	February 15, 2017
Completion date	December 31, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02917408` - Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital
Terminated	`NCT00550862` - Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)	Phase 2
Completed	`NCT00004748` - Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis	Phase 3
Completed	`NCT03630718` - Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women	N/A
Completed	`NCT00004842` - Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis	Phase 1
Terminated	`NCT03633227` - Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment	Phase 4
Terminated	`NCT00125281` - SAMe to Treat Biliary Cirrhosis Symptoms	Phase 2
Completed	`NCT04629456` - Physical Therapy for Liver Cirrhosis	N/A
Recruiting	`NCT03468699` - Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia	Phase 2
Completed	`NCT00004784` - Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis	Phase 3
Completed	`NCT00006168` - Ursodiol-Methotrexate for Primary Biliary Cirrhosis	Phase 3
Completed	`NCT00570765` - Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)	Phase 2
Recruiting	`NCT00160940` - Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	N/A
Terminated	`NCT03265249` - BRIDGE Device for Post-operative Pain Control	N/A
Terminated	`NCT02308111` - Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis	Phase 4
Recruiting	`NCT02936596` - Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome	N/A
Completed	`NCT00406237` - Pharmacokinetic Study Of Tigecycline In Adult Subjects With Primary Biliary Cirrhosis	Phase 1
Completed	`NCT04047160` - Safety, Tolerability of OP-724 in Patients With Primary Biliary Cholangitis (Phase I)	Phase 1
Recruiting	`NCT00145964` - Identification of the Genetic Variants Responsible for Primary Biliary Cirrhosis (PBC)	N/A
Terminated	`NCT03476993` - Non-comparative Study of BCD-085 in Combination With UDCA in Patients With Primary Biliary Cholangitis	Phase 2