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Liver Cirrhosis clinical trials

View clinical trials related to Liver Cirrhosis.

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NCT ID: NCT02868164 Withdrawn - Clinical trials for NASH Related Decompensated Cirrhosis

Fecal Microbiota Therapy Versus Standard Therapy in Decompensated NASH Related Cirrhosis: A Randomized Controlled Trial.

Start date: February 2018
Phase: N/A
Study type: Interventional

The study will be conducted in the Department of Hepatology, Institute of Liver & Biliary Sciences, New Delhi. As a part of this study history will be taken and clinical examination will be done. Subjects will be screened for diagnosis of NASH (Non Alcoholic Steatohepatitis) cirrhosis. If subjects are found to have NASH (Non Alcoholic Steatohepatitis) cirrhosis, they will be chosen to receive stool from healthy donor, which is voluntarily donated by a healthy donor related or unrelated to the subjects and the stool will be prepared using standard guidelines. The prepared sample of stool, about 50 ml will be instilled into proximal small intestine by way of a thin and soft tube inserted through nose. This administration of sample, 50 ml daily will occur once a month every month for 6 months. The liver function parameters will be assessed and thereafter at 1 month and 3 months & subjects will be clinically assessed for improvement or worsening.

NCT ID: NCT02837939 Withdrawn - Cirrhosis Clinical Trials

Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction

IMUNO-HEGITO7
Start date: July 2016
Phase: Phase 2/Phase 3
Study type: Interventional

This study is aimed to assess the efficacy of Human derived Transfer factor ( T-lymphocytes homogenate that contains small molecular weight (10 kDa) molecules: various IFNs, ILs, chemokines, endorfins, heat shock proteins) in decreasing rate and/or severity of infections in acute or chronic decompensations of liver cirrhosis and acute on chronic liver failure..

NCT ID: NCT02824354 Withdrawn - Cirrhosis Clinical Trials

Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence.

NalmeCir
Start date: December 1, 2018
Phase: Phase 3
Study type: Interventional

Nalmefene is the first drug to obtain Marketing Authorisation in France for reduction of alcohol consumption.

NCT ID: NCT02809248 Withdrawn - Clinical trials for Cirrhosis of the Liver

The Influence Cirrhosis of the Liver on the Coronary Re-stenosis (LTX- Stent Study)

Start date: July 2016
Phase: N/A
Study type: Interventional

The aim of the study is to choose an optimal stent and to get further knowledge about the mechanisms of the engraftment of a stent. The occurrence of a hyperplasia of neointima can be minimized by application of a coated stent and a concurrent safety four weekly dual thrombocytes therapy

NCT ID: NCT02739581 Withdrawn - Advanced Cirrhosis Clinical Trials

Efficacy and Safety of Endoscopic Variceal Ligation (EVL) Versus EVL Plus Non-selective B-blockers (NSBB) For Prevention of Variceal Rebleed and Non-bleed Related Complications in Patients With Advanced Cirrhosis

Start date: n/a
Phase: N/A
Study type: Interventional

The patients will be randomized into two groups 1. Endoscopic Variceal Ligation with Non Selective Beta Blocker 2. Placebo with Endoscopic Variceal Ligation

NCT ID: NCT02526303 Withdrawn - Liver Cirrhosis Clinical Trials

Anticoagulation for Non-occlusive Portal Vein Thrombosis in Patients With Liver Cirrhosis

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of anticoagulation in the treatment of non-occlusive portal vein thrombosis in patients with liver cirrhosis.

NCT ID: NCT02465619 Withdrawn - Cirrhosis Clinical Trials

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Start date: n/a
Phase: N/A
Study type: Observational

The study will be conducted on patients admitted to Department of Hepatology from MARCH 2015 to DECEMBER 2016 at ILBS, New Delhi.All patients presenting to ILBS fulfilling the inclusion criteria will be included in the study and will be categorized and evaluated. The patient will followed over a period of 3 months.

NCT ID: NCT02321306 Withdrawn - Clinical trials for Primary Biliary Cirrhosis

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis

CASCADE
Start date: May 2015
Phase: Phase 2
Study type: Interventional

Open-label, multicenter study in adults with Primary Biliary Cirrhosis (PBC) designed to evaluate the long-term safety and tolerability of daily dosing with LUM001.

NCT ID: NCT02289300 Withdrawn - Clinical trials for Hepatocellular Carcinoma

A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients

Start date: January 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether an investigational drug DCB-BO1202 is effective and safe in the treatment of liver fibrosis in HBV patients having experienced intermediate stage hepatocellular carcinoma (HCC)

NCT ID: NCT02275585 Withdrawn - Cirrhosis Clinical Trials

Portal Vein Thrombosis in Cirrhosis

Start date: October 2013
Phase: N/A
Study type: Observational

This study evaluates the supervivence of cirrhotic patients that develop portal vein thrombosis in comparison to cirrhotic patients that do not develop portal vein thrombosis.